SCHEMBL208288

SCHEMBL208288

Cc1cc(-n2nc3ccccc3n2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.64
RAB9A P51151 5/20 0.64
POLB P06746 3/20 0.57
LMNA P02545 1/20 0.56
ALDH1A1 P00352 5/20 0.50
SMN1; SMN2 Q16637 4/20 0.50
CA2 P00918 3/20 0.50
TYR P14679 1/20 0.50
KDM4E B2RXH2 3/20 0.43
HSPA5 P11021 1/20 0.42
CYP2C9 P11712 2/20 0.41
CYP2C19 P33261 2/20 0.41
HIF1A Q16665 2/20 0.41
TDP1 Q9NUW8 3/20 0.38
MAPT P10636 2/20 0.38
HPGD P15428 2/20 0.38
TSHR P16473 1/20 0.38
CYP2D6 P10635 1/20 0.38
HSD17B10 Q99714 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29365942 1.00 NPC1 (0.64) NPC1RAB9APOLBLMNAALDH1A1
Phenol SCHEMBL29086842 0.94 NPC1 (0.58) NPC1RAB9APOLBLMNAALDH1A1
Bumetrizole SCHEMBL6068328 0.90 NPC1 (0.60) NPC1RAB9APOLBLMNAALDH1A1
SCHEMBL2549469 0.88 NPC1 (0.50) NPC1RAB9APOLBLMNAALDH1A1
SCHEMBL6153043 0.88 HSPA5 (0.60) NPC1RAB9APOLBLMNAALDH1A1
SCHEMBL880931 0.87 NPC1 (0.49) NPC1RAB9APOLBLMNAALDH1A1
SCHEMBL22606033 0.87 NPC1 (0.50) NPC1RAB9APOLBLMNAALDH1A1
SCHEMBL7869116 0.86 NPC1 (0.50) NPC1RAB9APOLBLMNAALDH1A1
SCHEMBL8861272 0.86 NPC1 (0.58) NPC1RAB9APOLBLMNAALDH1A1
SCHEMBL17717937 0.86 NPC1 (0.58) NPC1RAB9APOLBLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1338 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6391949-B1 None US claimed
CN-119838184-A Multicomponent gas fire extinguishing agent composition, capsule-based flexible fire extinguishing patch and preparation method 天津航大天开科技发展有限公司 2025-04-18 CN claimed
CN-112608516-B Multifunctional light-stable composition and preparation method thereof 沈阳化工研究院有限公司 2022-04-08 CN claimed
CN-112608516-A Multifunctional light-stable composition and preparation method thereof 沈阳化工研究院有限公司 2021-04-06 CN claimed
US-10011095-B2 Synthetic resin laminate MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2018-07-03 US claimed
US-9988518-B2 Chlorine-resistant crosslinkable polyolefin compositions and articles made therefrom MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2018-06-05 US claimed
US-20150132518-A1 CHLORINE-RESISTANT CROSSLINKABLE POLYOLEFIN COMPOSITIONS AND ARTICLES MADE THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. 2015-05-14 US claimed
US-8962718-B2 Chlorine-resistant crosslinkable polyolefin compositions and articles made therefrom MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2015-02-24 US claimed
EP-1582549-B1 Flame retardant resin blends based on polymers derived from 2-hydrocarbyl-3,3-Bis(4-Hydroxyaryl)Phthalimidine monomers SABIC INNOVATIVE PLASTICS IP (NL) 2011-03-09 EP claimed
US-7326740-B2 Natural products composites CIBA SPECIALTY CHEMICALS CORPORATION (US) 2008-02-05 US claimed
US-6391949-B2 FOR AUTOMOBILE FINISHES; HEAT, OXIDATION, RADIATION RESISTANCE CIBA SPECIALTY CHEMICALS CORPORATION 2002-05-21 US claimed
US-20020058735-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith GALBO JAMES PETER (US) 2002-05-16 US claimed
US-6376584-B1 OXIDATION RESISTANCE, HEAT RESISTANCE, PHOTOSTABILITY CIBA SPECIALTY CHEMICALS CORPORATION 2002-04-23 US claimed
US-20010034449-A1 Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith GALBO JAMES P (US) 2001-10-25 US claimed
US-20010031872-A1 Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith GALBO JAMES P (US) 2001-10-18 US claimed
US-20010018520-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith GALBO JAMES P (US) 2001-08-30 US claimed
US-4986932-A SYNERGISTIC MIXTURE FOR LIGHT, HEAT AND OXIDATION RESISTANCE HUELS AKTIENGESELLSCHAFT (DE) 1991-01-22 US claimed
EP-0148648-B1 A METHOD FOR STABILIZING ALIPHATIC HIGHER ALDEHYDE COMPOUNDS Shin-Etsu Chemical Co., Ltd. (JP) 1987-07-22 EP claimed
US-4568771-A USING TERTIARY AMINE, BENZOPHENONE, SALICYLATE, BENZOTRIAZOLE, OR CYANOACRYLATE COMPOUNDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 1986-02-04 US claimed
EP-0148648-A1 A method for stabilizing aliphatic higher aldehyde compounds Shin-Etsu Chemical Co., Ltd. (JP) 1985-07-17 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020058735-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith OGG1, HAO2, POLH NPC1 1734/4885RAB9A 2375/4885POLB 153/4885
US-20010034449-A1 Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith POLH, OGG1, OGFOD1 NPC1 1790/4885RAB9A 2188/4885POLB 150/4885
US-20010018520-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith POLH, OGG1, OGFOD1 NPC1 1790/4885RAB9A 2188/4885POLB 150/4885
US-20010031872-A1 Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith POLH, OGG1, OGFOD1 NPC1 1790/4885RAB9A 2188/4885POLB 150/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.