Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bumetrizole SCHEMBL8056551 | 1.00 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| Bumetrizole SCHEMBL29353083 | 1.00 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| Bumetrizole SCHEMBL2398487 | 1.00 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| Bumetrizole SCHEMBL8603228 | 1.00 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| Bumetrizole SCHEMBL23734 | 1.00 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| Bumetrizole SCHEMBL9273939 | 0.99 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| Bumetrizole SCHEMBL6029618 | 0.99 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| Bumetrizole SCHEMBL9301984 | 0.99 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| Bumetrizole SCHEMBL10836210 | 0.99 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| Bumetrizole SCHEMBL6068328 | 0.96 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114174055-A | Method for making photochromic optical articles | 依视路国际公司 | 2022-03-11 | — | — | CN | disclosed |
| EP-3107730-A1 | MULTILAYER SHEET, METHODS FOR MAKING AND USING THE SAME, AND ARTICLES COMPRISING THE MULTILAYER SHEET | SABIC Global Technologies B.V. (NL) | 2016-12-28 | — | — | EP | disclosed |
| US-6077889-A | COMPOSITION COMPRISING THERMOPLASTIC POLYOLEFIN, MONOMERIC AND POLYMERIC HINDERED AMINE LIGHT STABILIZERS EACH HAVING PKA OF NO GREATER THAN 7, ULTRAVIOLET LIGHT ABSORBER | SOLVAY ENGINEERED POLYMERS (US) | 2000-06-20 | — | — | US | disclosed |
| US-6051637-A | MOLDED COMPOSITION THAT DOES NOT INTERFER WITH ACID CURATIVE COATINGS OF THERMOPLASTIC POLYOLEFIN, MONOMERIC AND POLYMERIC HINDERED AMINE LIGHT STABILIZER(HALS) HAVING A PKA OF NO GREATER THAN 7, AND AN ULTRAVIOLET LIGHT ABSORBER | SOLVAY ENGINEERED POLYMERS (US) | 2000-04-18 | — | — | US | disclosed |
| US-5716667-A | RELEASABLE AQUEOUS COATING BLEND CONTAINING AN ACRYLIC RESIN, ULTRAVIOLET LIGHT ABSORBER AND WATER REPELLENT | KANSAI PAINT CO., LTD. (JP) | 1998-02-10 | — | — | US | disclosed |