Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.46 |
| ▸ | GPR183 | P32249 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12655726 | 0.93 | L3MBTL1 (0.60) | L3MBTL1POLBHTTLMNAMAPT | |
| SCHEMBL12626093 | 0.86 | L3MBTL1 (0.54) | L3MBTL1POLBHTTLMNAMAPT | |
| SCHEMBL25495300 | 0.83 | HTT (0.56) | L3MBTL1POLBHTTLMNAMAPT | |
| SCHEMBL12621896 | 0.82 | HCRTR1 (0.56) | L3MBTL1LMNAMAPTSMN1; SMN2CA12 | |
| SCHEMBL12656050 | 0.80 | HCRTR1 (0.58) | L3MBTL1MAPTCA12CA1CA2 | |
| SCHEMBL12622095 | 0.80 | L3MBTL1 (0.68) | L3MBTL1POLBHTTLMNAMAPT | |
| SCHEMBL20362792 | 0.80 | ALDH1A1 (0.51) | L3MBTL1LMNAMAPTSMN1; SMN2HCRTR1 | |
| SCHEMBL12621865 | 0.80 | L3MBTL1 (0.68) | L3MBTL1POLBHTTLMNAMAPT | |
| SCHEMBL12622031 | 0.79 | HCRTR1 (0.55) | L3MBTL1MAPTCA12CA1CA2 | |
| SCHEMBL12656193 | 0.78 | L3MBTL1 (0.57) | L3MBTL1HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11661580-B2 | Method of inhibiting tau phosphorylation | CASSAVA SCIENCES, INC. (US) | 2023-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11661580-B2 | Method of inhibiting tau phosphorylation | FLNA, FLNB, MAPT | L3MBTL1 1789/4885POLB 2356/4885HTT 281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.