Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 18/20 | 0.67 |
| ▸ | HTR2C | P28335 | 17/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2553884 | 0.84 | HTR2A (0.50) | HTR2AHTR2CL3MBTL1ALDH1A1GAA | |
| SCHEMBL2553885 | 0.79 | SMN1; SMN2 (0.56) | ALDH1A1GAA | |
| SCHEMBL12315354 | 0.78 | HTR2A (0.74) | HTR2AHTR2CL3MBTL1ALDH1A1GAA | |
| SCHEMBL2555072 | 0.75 | KCNH2 (0.49) | ALDH1A1 | |
| SCHEMBL14625270 | 0.75 | HTR2A (0.76) | HTR2AHTR2CL3MBTL1ALDH1A1GAA | |
| SCHEMBL6034142 | 0.75 | HTR2A (0.76) | HTR2AHTR2CL3MBTL1ALDH1A1GAA | |
| SCHEMBL2338740 | 0.75 | HTR2A (1.00) | HTR2AHTR2CL3MBTL1ALDH1A1GAA | |
| SCHEMBL14045129 | 0.72 | HTR2A (0.44) | HTR2AHTR2CL3MBTL1ALDH1A1GAA | |
| SCHEMBL16627265 | 0.72 | HTR2A (0.70) | HTR2AHTR2CL3MBTL1ALDH1A1GAA | |
| SCHEMBL6034623 | 0.72 | HTR2A (0.72) | HTR2AHTR2CL3MBTL1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011121309-A1 | PHENYL SULFONYL DERIVATIVES AND THEIR USE AS HISTAMINE H3 ANTAGONISTS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-10-06 | — | — | WO | disclosed |