Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 10/20 | 0.50 |
| ▸ | HTR2C | P28335 | 10/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LSS | P48449 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | FABP6 | P51161 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2549845 | 0.84 | HTR2A (0.67) | HTR2AHTR2CALDH1A1GAAL3MBTL1 | |
| SCHEMBL7716908 | 0.79 | KDM4E (0.48) | ALDH1A1LMNAGAANAMPTHRH3 | |
| SCHEMBL2555109 | 0.79 | KDM4E (0.48) | ALDH1A1LMNAGAANAMPTHRH3 | |
| SCHEMBL2547933 | 0.79 | KDM4E (0.48) | ALDH1A1LMNAGAANAMPTHRH3 | |
| Hydrochloric Acid SCHEMBL2552429 | 0.78 | KDM4E (0.47) | ALDH1A1LMNAGAANAMPTHRH3 | |
| Hydrochloric Acid SCHEMBL2552428 | 0.78 | KDM4E (0.47) | ALDH1A1LMNAGAANAMPTHRH3 | |
| SCHEMBL2555154 | 0.76 | KDM4E (0.48) | OPRM1OPRK1ALDH1A1LMNAGAA | |
| SCHEMBL7716923 | 0.76 | SMN1; SMN2 (0.54) | ALDH1A1LMNAGAAHRH3FABP6 | |
| SCHEMBL2551564 | 0.76 | HRH3 (0.45) | OPRM1OPRK1ALDH1A1HRH3FABP6 | |
| SCHEMBL2553125 | 0.71 | SMN1; SMN2 (0.47) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011121309-A1 | PHENYL SULFONYL DERIVATIVES AND THEIR USE AS HISTAMINE H3 ANTAGONISTS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-10-06 | — | — | WO | disclosed |
| WO-2011121309-A1 | PHENYL SULFONYL DERIVATIVES AND THEIR USE AS HISTAMINE H3 ANTAGONISTS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-10-06 | — | — | WO | disclosed |