Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.35 |
| ▸ | PDE4A | P27815 | 3/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NCS1 | P62166 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 2/20 | 0.34 |
| ▸ | RAF1 | P04049 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25499207 | 0.91 | KDM4E (0.38) | HCRTR1HCRTR2MAPTSMN1; SMN2NPC1 | |
| SCHEMBL25501004 | 0.85 | BUB1 (0.41) | HCRTR1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL23720074 | 0.84 | NCS1 (0.43) | MAPTSMN1; SMN2NPC1RAB9ARXFP1 | |
| SCHEMBL31683884 | 0.84 | NCS1 (0.43) | MAPTSMN1; SMN2NPC1RAB9ARXFP1 | |
| SCHEMBL23719992 | 0.83 | ABL1 (0.43) | MAPTNPC1RAB9AKDM4ERXFP1 | |
| SCHEMBL31683921 | 0.83 | ABL1 (0.43) | MAPTNPC1RAB9AKDM4ERXFP1 | |
| SCHEMBL25500996 | 0.83 | ABL1 (0.42) | MAPTSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL21186127 | 0.81 | NPC1 (0.45) | HCRTR1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL21186103 | 0.81 | HCK (0.45) | MAPTNPC1RAB9AKDM4ERXFP1 | |
| SCHEMBL31683882 | 0.80 | ABL1 (0.41) | MAPTNPC1RAB9AKDM4ERXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230151023-A1 | PYRIDO[2,3-E]OXAZINE DERIVATIVES AS AGRICULTURAL CHEMICALS | GLOBACHEM NV (BE) | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230151023-A1 | PYRIDO[2,3-E]OXAZINE DERIVATIVES AS AGRICULTURAL CHEMICALS | PNPO, HPD, PDXK | HCRTR1 2530/4885HCRTR2 2441/4885MAPT 553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.