Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25502387 | 0.92 | SMN1; SMN2 (0.69) | HPGDSMN1; SMN2ALDH1A1RECQLHRH3 | |
| SCHEMBL4493181 | 0.82 | HRH3 (0.54) | HPGDSMN1; SMN2ALDH1A1RECQLHRH3 | |
| SCHEMBL4499465 | 0.82 | HRH3 (0.54) | HPGDSMN1; SMN2ALDH1A1RECQLHRH3 | |
| SCHEMBL750380 | 0.82 | HRH3 (0.54) | HPGDSMN1; SMN2ALDH1A1RECQLHRH3 | |
| SCHEMBL30885566 | 0.82 | HPGD (0.62) | HPGDSMN1; SMN2ALDH1A1RECQLHRH3 | |
| SCHEMBL10774942 | 0.81 | HRH3 (0.52) | HPGDSMN1; SMN2ALDH1A1RECQLHRH3 | |
| SCHEMBL1842901 | 0.79 | ALDH1A1 (0.50) | HPGDSMN1; SMN2ALDH1A1HRH3TSHR | |
| SCHEMBL8182758 | 0.79 | HPGD (0.51) | HPGDSMN1; SMN2ALDH1A1RECQLHRH3 | |
| SCHEMBL28595178 | 0.79 | HPGD (0.51) | HPGDSMN1; SMN2ALDH1A1RECQLHRH3 | |
| SCHEMBL27698678 | 0.79 | ALDH1A1 (0.50) | HPGDSMN1; SMN2ALDH1A1HRH3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086399-A1 | BIFUNCTIONAL DEGRADERS OF HEMATOPOIETIC PROGENITOR KINASE AND THERAPEUTIC USES THEREOF | NURIX THERAPEUTICS, INC. (US) | 2023-05-19 | — | — | WO | disclosed |