Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23816359 | 0.82 | SMN1; SMN2 (0.55) | SMN1; SMN2NPC1RAB9ACYP2C19HPGD | |
| SCHEMBL28106752 | 0.82 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RAB9ACYP2C19HPGD | |
| SCHEMBL28106751 | 0.82 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RAB9ACYP2C19HPGD | |
| SCHEMBL24131982 | 0.82 | SMN1; SMN2 (0.55) | SMN1; SMN2NPC1RAB9ACYP2C19HPGD | |
| SCHEMBL6642777 | 0.82 | SMN1; SMN2 (0.62) | SMN1; SMN2NPC1RAB9ACYP2C19HPGD | |
| SCHEMBL24131137 | 0.81 | L3MBTL1 (0.60) | SMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL24131658 | 0.81 | L3MBTL1 (0.60) | SMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL2356908 | 0.80 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9ACYP2C19PKM | |
| SCHEMBL15626857 | 0.80 | CHRM2 (0.54) | SMN1; SMN2NPC1RAB9ACYP2C19L3MBTL1 | |
| SCHEMBL13832812 | 0.80 | CHRM2 (0.54) | SMN1; SMN2NPC1RAB9ACYP2C19L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086399-A1 | BIFUNCTIONAL DEGRADERS OF HEMATOPOIETIC PROGENITOR KINASE AND THERAPEUTIC USES THEREOF | NURIX THERAPEUTICS, INC. (US) | 2023-05-19 | — | — | WO | disclosed |