Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 1/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28106751 | 1.00 | SMN1; SMN2 (0.56) | SMN1; SMN2CYP2C19NPC1RAB9AHPGD | |
| SCHEMBL28409668 | 0.92 | GABRA1 (0.53) | SMN1; SMN2CYP2C19NPC1RAB9AHPGD | |
| SCHEMBL18047420 | 0.91 | SMN1; SMN2 (0.58) | SMN1; SMN2CYP2C19NPC1RAB9AHPGD | |
| SCHEMBL23816359 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2CYP2C19NPC1RAB9AHPGD | |
| SCHEMBL6642777 | 0.83 | SMN1; SMN2 (0.62) | SMN1; SMN2CYP2C19NPC1RAB9AHPGD | |
| SCHEMBL24131982 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2CYP2C19NPC1RAB9AHPGD | |
| SCHEMBL24131137 | 0.82 | L3MBTL1 (0.60) | SMN1; SMN2NPC1RAB9ATSHRL3MBTL1 | |
| SCHEMBL24131658 | 0.82 | L3MBTL1 (0.60) | SMN1; SMN2NPC1RAB9ATSHRL3MBTL1 | |
| SCHEMBL25501916 | 0.82 | SMN1; SMN2 (0.53) | SMN1; SMN2CYP2C19NPC1RAB9AHPGD | |
| SCHEMBL15626857 | 0.81 | CHRM2 (0.54) | SMN1; SMN2CYP2C19NPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103764641-B | The tricyclic compound of fractional saturation and preparation and application thereof | 扎夫根股份有限公司 | 2016-10-26 | — | — | CN | disclosed |
| CN-1305454-A | Anthranilic acid derivatives as inhibitors of CGMP phosphodiesterase | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-07-25 | — | — | CN | disclosed |