⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28113982 | 0.97 | LMNA (0.70) | — | |
| E388 SCHEMBL28696 | 0.86 | LMNA (1.00) | — | |
| E388 SCHEMBL28962323 | 0.86 | LMNA (1.00) | — | |
| SCHEMBL7758720 | 0.85 | TSHR (0.58) | — | |
| Hydrochloric Acid SCHEMBL28534140 | 0.83 | BLM (0.56) | — | |
| SCHEMBL17633867 | 0.83 | NFKB1 (0.58) | — | |
| E388 SCHEMBL9715431 | 0.83 | LMNA (0.93) | — | |
| E388 SCHEMBL11415832 | 0.83 | LMNA (0.93) | — | |
| E388 SCHEMBL9715444 | 0.83 | LMNA (0.93) | — | |
| E388 SCHEMBL341724 | 0.83 | LMNA (0.93) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240366543-A1 | METHODS OF TREATING METHYLMALONIC ACIDEMIA AND PROPIONIC ACIDEMIA | HEMOSHEAR THERAPEUTICS INC (US) | 2024-11-07 | — | — | US | disclosed |
| EP-4319746-A1 | METHODS OF TREATING METHYLMALONIC ACIDEMIA AND PROPIONIC ACIDEMIA | Hemoshear Therapeutics, Inc. (US) | 2024-02-14 | — | — | EP | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| WO-2022216848-A1 | METHODS OF TREATING METHYLMALONIC ACIDEMIA AND PROPIONIC ACIDEMIA | Hemoshear Therapeutics, Inc. (US) | 2022-10-13 | — | — | WO | disclosed |
| US-11369568-B2 | Microparticles comprising a sulphur-containing compound | NOVABIOTICS LIMITED (GB) | 2022-06-28 | — | — | US | disclosed |
| US-20220142955-A1 | METHODS OF TREATING ORGANIC ACIDEMIAS | Hemoshear Therapeutics, Inc. | 2022-05-12 | — | — | US | disclosed |
| CN-110283329-B | Special superplasticizer for machine-made sand concrete and preparation method thereof | 江苏苏博特新材料股份有限公司 | 2022-04-22 | — | — | CN | disclosed |
| CN-110372827-B | Concrete superplasticizer and preparation method thereof | 江苏苏博特新材料股份有限公司 | 2022-03-18 | — | — | CN | disclosed |
| EP-3937922-A1 | METHODS OF TREATING ORGANIC ACIDEMIAS | Hemoshear Therapeutics, Inc. (US) | 2022-01-19 | — | — | EP | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| US-20120202890-A1 | POLYMER-CARBOHYDRATE-LIPID CONJUGATES | WU NIAN (US) | 2012-08-09 | — | — | US | disclosed |
| US-20120202979-A1 | POLYMER-CARBOHYDRATE-LIPID CONJUGATES | LIPOSEUTICALS, INC. | 2012-08-09 | — | — | US | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |
| US-20110040113-A1 | Pure PEG-lipid conjugates | WU NIAN | 2011-02-17 | — | — | US | disclosed |
| US-20110033527-A1 | Opthalmic compositions of cyclosporin | WU NIAN | 2011-02-10 | — | — | US | disclosed |
| US-20100240883-A1 | Lipid-drug conjugates for drug delivery | WU NIAN | 2010-09-23 | — | — | US | disclosed |
| US-5391564-A | E.g., rhizoxin-13-yl 3-methylthiopropionate; anticarcinogenic agents | SANKYO COMPANY, LIMITED (JP) | 1995-02-21 | — | — | US | disclosed |
| US-5352689-A | Rhizoxin derivatives and their use as anti-tumor agents | SANKYO COMPANY, LIMITED (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0350315-B1 | RHIZOXIN DERIVATES AND THEIR USE AS ANTI-TUMOR AGENTS | SANKYO COMPANY LIMITED (JP) | 1993-06-16 | — | — | EP | disclosed |
| EP-0350315-A1 | Rhizoxin derivates and their use as anti-tumor agents | SANKYO COMPANY LIMITED (JP) | 1990-01-10 | — | — | EP | disclosed |