SCHEMBL2550700

SCHEMBL2550700

CS(=O)(=O)c1cnccn1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC40A1 Q9NP59 1/20 0.39
HSP90AA1 P07900 1/20 0.37
KDM4E B2RXH2 2/20 0.37
NAPRT Q6XQN6 1/20 0.37
HCAR2 Q8TDS4 1/20 0.37
LMNA P02545 2/20 0.37
POLB P06746 1/20 0.37
GLA P06280 1/20 0.37
ABCC9 O60706 1/20 0.36
ABCC8 Q09428 1/20 0.36
KCNJ11 Q14654 1/20 0.36
KCNJ8 Q15842 1/20 0.36
GPR119 Q8TDV5 1/20 0.36
ADORA3 P0DMS8 1/20 0.35
TSHR P16473 1/20 0.35
MC4R P32245 1/20 0.35
ADRA1A P35348 1/20 0.35
MC3R P41968 1/20 0.35
NLRP3 Q96P20 1/20 0.35
PTGS2 P35354 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrazine SCHEMBL27587071 0.96 HSP90AA1 (0.39) SLC40A1HSP90AA1KDM4ENAPRTHCAR2
SCHEMBL7835984 0.80 SLC40A1 (0.41) SLC40A1HSP90AA1KDM4ENAPRTHCAR2
SCHEMBL20161743 0.80 HSP90AA1 (0.40) SLC40A1HSP90AA1KDM4ENAPRTHCAR2
SCHEMBL329658 0.78 SLC40A1 (0.40) SLC40A1HSP90AA1KDM4ENAPRTHCAR2
SCHEMBL12655512 0.77 HSP90AA1 (0.39) SLC40A1HSP90AA1KDM4ENAPRTHCAR2
SCHEMBL19260832 0.76 CA12 (0.36) LMNAPOLBGPR119CA12CA1
SCHEMBL1076499 0.76 CA12 (0.43) SLC40A1HSP90AA1KDM4ENAPRTHCAR2
SCHEMBL22001834 0.76 HSP90AA1 (0.37) SLC40A1HSP90AA1KDM4ENAPRTHCAR2
SCHEMBL20019666 0.76 SLC40A1 (0.39) SLC40A1HSP90AA1KDM4ENAPRTHCAR2
SCHEMBL3155945 0.76 SLC40A1 (0.39) SLC40A1HSP90AA1KDM4ENAPRTHCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102464661-B Preparation method of 5,6,7,8-tetrahydro-imidazo[1,5-a]pyrazine-1-carboxylic acid ethyl ester WUXI APPTEC TIANJIN CO LTD 2015-04-01 CN claimed
CN-102464661-A Preparation method of 5,6,7, 8-tetrahydro-imidazo [1,5-a ] pyrazine-1-carboxylic acid ethyl ester WUXI APPTEC CO LTD 2012-05-23 CN claimed
US-12471596-B2 Substituted 6-membered heteroaryl piperidinyl ethanones PI INDUSTRIES LTD. (IN) 2025-11-18 US disclosed
CN-117425470-A Antiperspirant compositions 科蒂公司 2024-01-19 CN disclosed
CN-116940326-A Antiperspirant compositions 科蒂公司 2023-10-24 CN disclosed
CN-116367811-A Antiperspirant compositions 科蒂公司 2023-06-30 CN disclosed
US-20230031192-A1 NOVEL SUBSTITUTED 6- MEMBERED HETEROARYL PIPERIDINYL ETHANONES PI INDUSTRIES LTD. (IN) 2023-02-02 US disclosed
CN-113348243-A Method for separating and culturing human retinal progenitor cells 加利福尼亚大学董事会 2021-09-03 CN disclosed
EP-2918587-B1 Filamin A binding compounds and their use as anti-inflammatory and analgesic agents PAIN THERAPEUTICS INC (US) 2018-04-04 EP disclosed
CN-104220426-B Estrogen receptor modulators and uses thereof 塞拉根制药公司 2017-03-01 CN disclosed
EP-2488177-B1 FILAMIN A BINDING ANTI-INFLAMMATORY AND ANALGESIC PAIN THERAPEUTICS INC (US) 2016-10-12 EP disclosed
US-20070184386-A1 Optical recording material and optical recording medium MITSUBISHI CHEMICAL CORPORATION (JP) 2007-08-09 US disclosed
US-7244486-B2 Optical recording medium and optical recording method MITSUBISHI CHEMICAL CORPORATION (JP) 2007-07-17 US disclosed
US-7244486-B2 Optical recording medium and optical recording method MITSUBISHI CHEMICAL CORPORATION (JP) 2007-07-17 US disclosed
US-20070054219-A1 Azo-metal chelate dye and optical recording medium MITSUBISHI KAGAKU MEDIA CO., LTD. (JP) 2007-03-08 US disclosed
US-20070054219-A1 Azo-metal chelate dye and optical recording medium MITSUBISHI KAGAKU MEDIA CO., LTD. (JP) 2007-03-08 US disclosed
EP-1233959-A1 HETEROCYCLO-ALKYLSULFONYL PYRAZOLE DERIVATIVES AS ANTI-INFLAMMATORY/ANALGESIC AGENTS Pfizer Products Inc. (US) 2002-08-28 EP disclosed
WO-2001040216-A1 HETEROCYCLO-ALKYLSULFONYL PYRAZOLE DERIVATIVES AS ANTI-INFLAMMATORY/ANALGESIC AGENTS PFIZER PRODUCTS INC. (US) 2001-06-07 WO disclosed
US-5776858-A HERBICIDES NIHON BAYER AGROCHEM K.K. (JP) 1998-07-07 US disclosed
EP-0771797-A1 1-Azinyl-tetrazolinone herbicides NIHON BAYER AGROCHEM K.K. (JP) 1997-05-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12471596-B2 Substituted 6-membered heteroaryl piperidinyl ethanones CCNK, CCNA1, CYP1A1 SLC40A1 3012/4885HSP90AA1 1850/4885KDM4E 1010/4885
US-20230031192-A1 NOVEL SUBSTITUTED 6- MEMBERED HETEROARYL PIPERIDINYL ETHANONES CCNK, CYP1B1, CYP1A1 SLC40A1 3156/4885HSP90AA1 1800/4885KDM4E 1130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.