Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.40 |
| ▸ | L3MBTL3 | Q96JM7 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24802271 | 0.89 | L3MBTL3 (0.37) | ALDH1A1HRH3L3MBTL3L3MBTL1 | |
| SCHEMBL24480231 | 0.87 | HRH3 (0.35) | ALDH1A1HRH3L3MBTL3L3MBTL1 | |
| SCHEMBL26743257 | 0.84 | ALDH1A1 (0.34) | ALDH1A1HRH3L3MBTL3L3MBTL1 | |
| SCHEMBL24940901 | 0.84 | KDM4E (0.33) | HRH3L3MBTL3L3MBTL1KDM4ETDP1 | |
| SCHEMBL24480841 | 0.83 | HRH3 (0.37) | ALDH1A1HRH3L3MBTL3L3MBTL1KDM4E | |
| SCHEMBL25511877 | 0.83 | HRH3 (0.37) | ALDH1A1HRH3L3MBTL3L3MBTL1 | |
| SCHEMBL27393320 | 0.82 | OPRL1 (0.33) | HRH3L3MBTL3L3MBTL1KDM4ETDP1 | |
| SCHEMBL14996489 | 0.82 | ALDH1A1 (0.38) | ALDH1A1HRH3L3MBTL3L3MBTL1 | |
| SCHEMBL4400116 | 0.82 | ALDH1A1 (0.52) | ALDH1A1L3MBTL3L3MBTL1KDM4ETDP1 | |
| SCHEMBL26743274 | 0.81 | HRH3 (0.36) | ALDH1A1HRH3L3MBTL3L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4180427-A1 | COMPOUND CAPABLE OF INHIBITING AND DEGRADING ANDROGEN RECEPTORS, AND PHARMACEUTICAL COMPOSITIONS AND PHARMACEUTICAL USES THEREOF | Sichuan Haisco Pharmaceutical Co., Ltd. (CN) | 2023-05-17 | — | — | EP | disclosed |