SCHEMBL24940901

SCHEMBL24940901

CN1CCC2(CC1)CC(N1CCCC1)C2

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
HRH3 Q9Y5N1 5/20 0.33
L3MBTL3 Q96JM7 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
OPRL1 P41146 2/20 0.31
FYN P06241 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27393320 0.98 OPRL1 (0.33) KDM4ETDP1HRH3L3MBTL3L3MBTL1
SCHEMBL24185878 0.89 KDM4E (0.34) KDM4ETDP1HRH3
SCHEMBL25471070 0.88 HRH3 (0.32) HRH3
SCHEMBL24185416 0.87 CYP3A4 (0.31)
SCHEMBL25507635 0.84 ALDH1A1 (0.40) KDM4ETDP1HRH3L3MBTL3L3MBTL1
SCHEMBL25508556 0.83 HRH3 (0.32) HRH3
SCHEMBL22737160 0.83 HRH3 (0.32) HRH3
SCHEMBL24802271 0.83 L3MBTL3 (0.37) HRH3L3MBTL3L3MBTL1
SCHEMBL24480648 0.82 POLB (0.33) KDM4ETDP1HRH3
SCHEMBL23867411 0.82 HTR6 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023006088-A1 COMPOUND FOR EGFR KINASE INHIBITOR, COMPOSITION AND USE THEREOF 浙江大学智能创新药物研究院 2023-02-02 WO disclosed