Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.41 |
| ▸ | DRD2 | P14416 | 6/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12705088 | 0.90 | CACNA1H (0.53) | CACNA1HALDH1A1KDM4EMEN1GAA | |
| SCHEMBL16749992 | 0.83 | CACNA1H (0.47) | CACNA1HALDH1A1KDM4EMEN1GAA | |
| SCHEMBL18545131 | 0.83 | CACNA1H (0.47) | CACNA1HALDH1A1KDM4EMEN1GAA | |
| SCHEMBL16749955 | 0.83 | CACNA1H (0.47) | CACNA1HALDH1A1KDM4EMEN1GAA | |
| SCHEMBL7127556 | 0.80 | ALDH1A1 (0.51) | ALDH1A1KDM4EMEN1GAAKMT2A | |
| SCHEMBL23869826 | 0.80 | ALDH1A1 (0.47) | CACNA1HALDH1A1KDM4EKMT2ATDP1 | |
| SCHEMBL23153012 | 0.80 | ALDH1A1 (0.51) | ALDH1A1KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL14288943 | 0.80 | KDM4E (0.60) | ALDH1A1KDM4EKMT2ATDP1SIGMAR1 | |
| SCHEMBL24709383 | 0.80 | ALDH1A1 (0.47) | ALDH1A1KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL27331967 | 0.80 | ALDH1A1 (0.47) | ALDH1A1KDM4EMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230144534-A1 | CLEAVABLE TETRAZINE USED IN BIO-ORTHOGONAL DRUG ACTIVATION | TAGWORKS PHARMACEUTICALS B.V. (NL) | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230144534-A1 | CLEAVABLE TETRAZINE USED IN BIO-ORTHOGONAL DRUG ACTIVATION | KIT, TPSB2, BTD | CACNA1H 1918/4885ALDH1A1 760/4885KDM4E 2183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.