SCHEMBL2551206

SCHEMBL2551206

C=CC(=O)NCCC(NC)(NC)NC

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 1/20 0.48
ZDHHC2 Q9UIJ5 1/20 0.48
TSHR P16473 2/20 0.46
ALDH1A1 P00352 2/20 0.46
MAPK1 P28482 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
GAA P10253 1/20 0.39
TGM2 P21980 2/20 0.33
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3390316 0.98 ZDHHC20 (0.47) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
Sulfuric Acid SCHEMBL6812276 0.93 ZDHHC20 (0.47) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL4653768 0.89 ZDHHC20 (0.55) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL2151789 0.81 TSHR (0.52) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL6283366 0.79 ZDHHC20 (0.52) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL1323810 0.79 ALDH1A1 (0.50) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL4387233 0.78 ZDHHC20 (0.47) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL12731248 0.78 ZDHHC20 (0.50) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL4080615 0.77 TSHR (0.43) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL24932662 0.76 ZDHHC20 (0.48) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0119109-B2 CATIONIC AQUEOUS DISPERSIONS OF SYNTHETIC POLYMERS RHONE-POULENC CHIMIE (FR) 1991-06-19 EP claimed
US-4857585-A CATIONIC ACRYLIC POLYMERS RHONE-POULENC SPECIALITIES CHIMIQUES (FR) 1989-08-15 US claimed
EP-0118326-B1 STABLE AMPHOTERIC LATICES FROM CONJUGATED DIENES RHONE-POULENC CHIMIE (FR) 1987-07-01 EP claimed
EP-0119109-B1 CATIONIC AQUEOUS DISPERSIONS OF SYNTHETIC POLYMERS RHONE-POULENC CHIMIE (FR) 1987-07-01 EP claimed
EP-0118327-B1 CATIONIC LATICES FROM CONJUGATED DIENES RHONE-POULENC CHIMIE (FR) 1987-04-22 EP claimed
EP-0120720-B1 STABLE AND AMPHOTERIC AQUEOUS DISPERSION OF SYNTHETIC POLYMERS RHONE-POULENC CHIMIE (FR) 1987-04-08 EP claimed
US-4528322-A Aqueous cationic dispersions of synthetic polymers RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1985-07-09 US claimed
EP-0120720-A1 Stable and amphoteric aqueous dispersion of synthetic polymers RHONE-POULENC CHIMIE (FR) 1984-10-03 EP claimed
EP-0119109-A1 Cationic aqueous dispersions of synthetic polymers RHONE-POULENC CHIMIE (FR) 1984-09-19 EP claimed
EP-0118327-A1 Cationic latices from conjugated dienes RHONE-POULENC CHIMIE (FR) 1984-09-12 EP claimed
EP-0118326-A1 Stable amphoteric latices from conjugated dienes RHONE-POULENC CHIMIE (FR) 1984-09-12 EP claimed
US-11607407-B2 Dermal pharmaceutical compositions of 1-methyl-2′,6′-pipecoloxylidide and method of use RELMADA THERAPEUTICS, INC. (US) 2023-03-21 US disclosed
CN-107115326-B Skin pharmaceutical composition of 1-methyl-N- (2, 6-xylyl) -2-piperidine formamide and using method thereof 雷尔玛达治疗股份有限公司 2021-01-22 CN disclosed
EP-2557924-B1 DERMAL PHARMACEUTICAL COMPOSITIONS OF 1-METHYL-2',6'-PIPECOLOXYLIDIDE AND METHOD OF USE RELMADA THERAPEUTICS INC (US) 2019-06-12 EP disclosed
US-20170333410-A1 Dermal Pharmaceutical Compositions of 1-Methyl-2',6'-Pipecoloxylidide and Method of Use RELMADA THERAPEUTICS, INC. (US) 2017-11-23 US disclosed
US-4528322-A Aqueous cationic dispersions of synthetic polymers RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1985-07-09 US disclosed
EP-0120720-A1 Stable and amphoteric aqueous dispersion of synthetic polymers RHONE-POULENC CHIMIE (FR) 1984-10-03 EP disclosed
EP-0119109-A1 Cationic aqueous dispersions of synthetic polymers RHONE-POULENC CHIMIE (FR) 1984-09-19 EP disclosed
EP-0118326-A1 Stable amphoteric latices from conjugated dienes RHONE-POULENC CHIMIE (FR) 1984-09-12 EP disclosed
EP-0118327-A1 Cationic latices from conjugated dienes RHONE-POULENC CHIMIE (FR) 1984-09-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170333410-A1 Dermal Pharmaceutical Compositions of 1-Methyl-2',6'-Pipecoloxylidide and Method of Use PIP4K2C, PIP5K1C, PIP4K2A ZDHHC20 607/4885ZDHHC2 1105/4885TSHR 4874/4885
US-11607407-B2 Dermal pharmaceutical compositions of 1-methyl-2′,6′-pipecoloxylidide and method of use PIP4K2C, PIP5K1C, PIP4K2A ZDHHC20 579/4885ZDHHC2 1036/4885TSHR 4874/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.