SCHEMBL4387233

SCHEMBL4387233

C=CC(=O)NCCCC(NC)(NC)NC.COS(=O)(=O)O

nearest known ligand 0.47

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 1/20 0.47
ZDHHC2 Q9UIJ5 1/20 0.47
TGM2 P21980 9/20 0.36
GAA P10253 1/20 0.36
ALDH1A1 P00352 1/20 0.34
TSHR P16473 1/20 0.34
MAPK1 P28482 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
HTR1A P08908 2/20 0.32
HTR2C P28335 2/20 0.32
HTR2A P28223 1/20 0.32
SLC6A4 P31645 1/20 0.32
HTR7 P34969 1/20 0.32
HTR6 P50406 1/20 0.32
MAPT P10636 1/20 0.31
TYR P14679 1/20 0.31
PSMB11 A5LHX3 1/20 0.30
PSMA7 O14818 1/20 0.30
PSMB1 P20618 1/20 0.30
PSMA1 P25786 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4653768 0.88 ZDHHC20 (0.55) ZDHHC20ZDHHC2TGM2GAAALDH1A1
SCHEMBL1127677 0.82 ZDHHC20 (0.53) ZDHHC20ZDHHC2TGM2GAAALDH1A1
Sulfuric Acid SCHEMBL6812276 0.82 ZDHHC20 (0.47) ZDHHC20ZDHHC2TGM2GAAALDH1A1
SCHEMBL4393922 0.80 KDM4E (0.31) MAPK1
SCHEMBL17255890 0.79 ZDHHC20 (0.40) ZDHHC20ZDHHC2TGM2GAAALDH1A1
SCHEMBL2551206 0.78 ZDHHC20 (0.48) ZDHHC20ZDHHC2TGM2GAAALDH1A1
SCHEMBL15846309 0.77 ZDHHC20 (0.58) ZDHHC20ZDHHC2TGM2GAAALDH1A1
Trimethylammonium SCHEMBL1232298 0.77 ZDHHC20 (0.63) ZDHHC20ZDHHC2TGM2ALDH1A1TSHR
Trimethylammonium SCHEMBL27979802 0.77 ZDHHC20 (0.63) ZDHHC20ZDHHC2TGM2ALDH1A1TSHR
SCHEMBL127108 0.77 ZDHHC20 (0.50) ZDHHC20ZDHHC2TGM2GAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4791161-A CONTAINING UNSATURATED TERTIARY NITROGEN COMPOUNDS RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1988-12-13 US claimed
US-4525519-A POLYMERIZATION IN AQUEOUS DISPERSION OF UNSATURATED NITROGEN COMPOUND AND CATIONIC EMULSION RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1985-06-25 US claimed
US-8883262-B2 Modification of solid surfaces by application of polymer associations thereon RHODIA OPERATIONS (FR) 2014-11-11 US disclosed
US-20090306292-A1 MODIFICATION OF SOLID SURFACES BY APPLICATION OF POLYMER ASSOCIATIONS THEREON RHODIA RECHERCHES ET TECHNOLOGIES (FR) 2009-12-10 US disclosed
US-4791161-A CONTAINING UNSATURATED TERTIARY NITROGEN COMPOUNDS RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1988-12-13 US disclosed
US-4525519-A POLYMERIZATION IN AQUEOUS DISPERSION OF UNSATURATED NITROGEN COMPOUND AND CATIONIC EMULSION RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1985-06-25 US disclosed