Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.48 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | STAT1 | P42224 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2548727 | 0.95 | ALDH1A1 (0.45) | DHODHPLA2G2AELANEL3MBTL1GAA | |
| SCHEMBL30271650 | 0.79 | KDM4E (0.48) | DHODHGAASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL30271652 | 0.79 | KDM4E (0.48) | DHODHGAASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL5400497 | 0.79 | PLA2G2A (0.65) | DHODHPLA2G2AL3MBTL1GAAPDE10A | |
| SCHEMBL31310820 | 0.79 | PLA2G2A (0.65) | DHODHPLA2G2AL3MBTL1GAAPDE10A | |
| SCHEMBL23271888 | 0.79 | ELANE (0.57) | ELANEL3MBTL1ALDH1A1LMNATSHR | |
| SCHEMBL21065456 | 0.77 | KDM4E (0.51) | DHODHGAASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL21065472 | 0.77 | KDM4E (0.51) | DHODHGAASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL28383797 | 0.77 | ELANE (0.59) | ELANEL3MBTL1GAAALDH1A1RAB9A | |
| SCHEMBL247426 | 0.76 | LMNA (0.51) | DHODHPDE10ASMN1; SMN2ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2556078-B1 | CATALYSTS FOR ALKYNE METATHESIS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2014-09-24 | — | — | EP | claimed |
| EP-2556078-A1 | CATALYSTS FOR ALKYNE METATHESIS | Studiengesellschaft Kohle MbH (DE) | 2013-02-13 | — | — | EP | claimed |
| WO-2011120508-A1 | CATALYSTS FOR ALKYNE METATHESIS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2011-10-06 | — | — | WO | claimed |
| EP-1449580-B1 | Production method of a cross-coupling compound from an alkyl halide and an organoboron compound | SUMITOMO CHEMICAL CO (JP) | 2005-12-28 | — | — | EP | claimed |
| EP-2680967-B1 | MOLYBDENUM AND TUNGSTEN METAL COMPLEXES AND USE THEREOF AS PRECATALYSTS FOR OLEFIN METATHESIS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2015-05-13 | — | — | EP | disclosed |
| EP-2556078-B1 | CATALYSTS FOR ALKYNE METATHESIS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2014-09-24 | — | — | EP | disclosed |
| EP-2680967-A1 | MOLYBDENUM AND TUNGSTEN METAL COMPLEXES AND USE THEREOF AS PRECATALYSTS FOR OLEFIN METATHESIS | Studiengesellschaft Kohle MbH (DE) | 2014-01-08 | — | — | EP | disclosed |
| EP-2556078-A1 | CATALYSTS FOR ALKYNE METATHESIS | Studiengesellschaft Kohle MbH (DE) | 2013-02-13 | — | — | EP | disclosed |
| WO-2012116695-A1 | MOLYBDENUM AND TUNGSTEN METAL COMPLEXES AND USE THEREOF AS PRECATALYSTS FOR OLEFIN METATHESIS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2012-09-07 | — | — | WO | disclosed |
| WO-2011120508-A1 | CATALYSTS FOR ALKYNE METATHESIS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2011-10-06 | — | — | WO | disclosed |