Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 18/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25512534 | 0.83 | GPR139 (0.42) | GPR139 | |
| SCHEMBL25512531 | 0.81 | GPR139 (0.37) | GPR139 | |
| SCHEMBL25515242 | 0.80 | GPR139 (0.53) | GPR139 | |
| SCHEMBL25208442 | 0.78 | GPR139 (0.38) | GPR139 | |
| SCHEMBL22226406 | 0.78 | GPR139 (0.38) | GPR139 | |
| SCHEMBL30813765 | 0.75 | BRD9 (0.49) | GPR139 | |
| SCHEMBL25512533 | 0.74 | GPR139 (0.33) | GPR139 | |
| SCHEMBL10278288 | 0.72 | GPR139 (0.49) | GPR139 | |
| SCHEMBL19966735 | 0.72 | MET (0.38) | GPR139 | |
| SCHEMBL21025997 | 0.67 | TDP1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088425-A1 | 15-PGDH INHIBITOR AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2023-05-25 | — | — | WO | disclosed |