Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25512531 | 0.79 | GPR139 (0.37) | GPR139MAPT | |
| SCHEMBL25199276 | 0.78 | AHR (0.33) | — | |
| SCHEMBL25512535 | 0.74 | GPR139 (0.44) | GPR139 | |
| SCHEMBL24820619 | 0.70 | KCNH2 (0.38) | GPR139MAPTKCNH2 | |
| SCHEMBL25512534 | 0.69 | GPR139 (0.42) | GPR139 | |
| SCHEMBL24819773 | 0.68 | KCNH2 (0.39) | GPR139KCNH2 | |
| SCHEMBL19879926 | 0.67 | HSD11B1 (0.39) | MAPTL3MBTL1KCNH2 | |
| SCHEMBL21025997 | 0.65 | TDP1 (0.43) | MAPTJAK2 | |
| SCHEMBL15341830 | 0.62 | DNMT1 (0.40) | — | |
| SCHEMBL22358063 | 0.62 | PIK3CD (0.36) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088425-A1 | 15-PGDH INHIBITOR AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2023-05-25 | — | — | WO | disclosed |