Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | ESR1 | P03372 | 4/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | CA4 | P22748 | 4/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CA3 | P07451 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30759711 | 1.00 | TDP1 (0.52) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL31325611 | 0.98 | ESR1 (0.50) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL5596874 | 0.95 | TDP1 (0.52) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL31003837 | 0.89 | ESR1 (0.43) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL7598255 | 0.88 | ESR1 (0.42) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| Phosphoric Acid SCHEMBL30084858 | 0.85 | ESR1 (0.43) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL18486570 | 0.84 | ESR1 (0.46) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL3934481 | 0.84 | ESR1 (0.46) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL3070052 | 0.84 | ALDH1A1 (0.53) | TDP1CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL25060869 | 0.82 | ESR1 (0.40) | TDP1CYP3A4ESR1ESR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 352 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250122269-A1 | SELECTIVE REDUCTION OF ANTIBODIES | ABBVIE INC (US) | 2025-04-17 | — | — | US | claimed |
| CN-119488608-A | Engineering bispecific antibody coupling drug and preparation method and application thereof | 上海药明合联生物技术有限公司 | 2025-02-21 | — | — | CN | claimed |
| CN-119213022-A | Preparation method of antibody-drug conjugate | 上海迈晋生物医药科技有限公司 | 2024-12-27 | — | — | CN | claimed |
| CN-117838879-B | Preparation method for improving homogeneity of antibody-drug conjugate and application thereof | 上海药明合联生物技术有限公司 | 2024-11-01 | — | — | CN | claimed |
| CN-117838879-A | Preparation method for improving homogeneity of antibody-drug conjugate and application thereof | 上海药明合联生物技术有限公司 | 2024-04-09 | — | — | CN | claimed |
| CN-117384211-A | Titanium catalyst for polyester synthesis and preparation method and application thereof | 江苏瑞祥化工有限公司 | 2024-01-12 | — | — | CN | claimed |
| WO-2023222108-A1 | METHOD FOR PREPARING ANTIBODY-DRUG CONJUGATE | 上海迈晋生物医药科技有限公司 | 2023-11-23 | — | — | WO | claimed |
| US-11780864-B2 | Rhenium(V) alkylidyne complexes and methods of use and preparation thereof | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2023-10-10 | — | — | US | claimed |
| US-20230059662-A1 | Rhenium(V) Alkylidyne Complexes and Methods of Use and Preparation Thereof | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2023-02-23 | — | — | US | claimed |
| CN-108069987-B | Method for producing fused heteroaromatic compound, electronic device, intermediate, and method for producing same | 三星电子株式会社 | 2022-03-22 | — | — | CN | claimed |
| US-20080217582-A1 | CLASS OF LUMINESCENT IRIDIUM(III) COMPLEXES WITH 2-(DIPHENYLPHOSPHINO)PHENOLATE LIGAND AND ORGANIC ELECTROLUMINESCENT DEVICE THEREOF | CHI, YUN (TW) | 2008-09-11 | — | — | US | claimed |
| EP-0699702-A2 | Reaction products of carbonyl compounds and dihydric phenols | THE DOW CHEMICAL COMPANY (US) | 1996-03-06 | — | — | EP | claimed |
| EP-0128597-B1 | ETHYLENE OLIGOMERIZATION PROCESS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1987-10-07 | — | — | EP | claimed |
| EP-0128596-B1 | ETHYLENE OLIGOMERIZATION PROCESS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1987-05-20 | — | — | EP | claimed |
| US-4503279-A | NICKEL CATALYST FORMED IN SITU | SHELL OIL COMPANY (US) | 1985-03-05 | — | — | US | claimed |
| US-4503280-A | NICKEL COMPLEX CATALYST | SHELL OIL COMPANY (US) | 1985-03-05 | — | — | US | claimed |
| EP-0128597-A2 | Ethylene oligomerization process | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1984-12-19 | — | — | EP | claimed |
| EP-0128596-A2 | Ethylene oligomerization process | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1984-12-19 | — | — | EP | claimed |
| US-4472525-A | POLYMERIZATION CATALYST CONSISTING OF NICKEL COMPOUND AND O-DIHYDROCARBYLPHOSPHINOPHENYL ALCOHOL ETHER | SHELL OIL COMPANY (US) | 1984-09-18 | — | — | US | claimed |
| US-4472522-A | SUING POLYMERIZATION CATALYST COMPOSITION OF NICKEL SALT, BORON HYDRIDE REDUCING AGENT, AND O-DIHYDROCARBYLPHOSPHINOPHENYL ALCOHOL OR ETHER | SHELL OIL COMPANY (US) | 1984-09-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230059662-A1 | Rhenium(V) Alkylidyne Complexes and Methods of Use and Preparation Thereof | RNF168, CCND2, RAD50 | TDP1 2906/4885CYP3A4 490/4885ESR1 1464/4885 |
| US-11780864-B2 | Rhenium(V) alkylidyne complexes and methods of use and preparation thereof | RNF168, CCND2, RAD50 | TDP1 2906/4885CYP3A4 490/4885ESR1 1464/4885 |
| US-20250122269-A1 | SELECTIVE REDUCTION OF ANTIBODIES | CD2BP2, CD22, CD2 | TDP1 2072/4885CYP3A4 3960/4885ESR1 3194/4885 |
| US-20080217582-A1 | CLASS OF LUMINESCENT IRIDIUM(III) COMPLEXES WITH 2-(DIPHENYLPHOSPHINO)PHENOLATE LIGAND AND ORGANIC ELECTROLUMINESCENT DEVICE THEREOF | IK, ITPR3, ITPR2 | TDP1 4125/4885CYP3A4 2560/4885ESR1 466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.