Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 5/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | PHLPP1 | O60346 | 1/20 | 0.33 |
| ▸ | ILK | Q13418 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25513582 | 0.91 | AKT1 (0.40) | AKT1BCHERXRACOXFA4KDM4E | |
| SCHEMBL25513495 | 0.86 | AKT1 (0.46) | AKT1BCHERXRAPPARGPPARD | |
| SCHEMBL25513578 | 0.84 | IRAK4 (0.36) | AKT1KDM4EHTTATMIRAK4 | |
| SCHEMBL15898925 | 0.83 | AKT1 (0.47) | AKT1BCHERXRAPPARGPPARD | |
| SCHEMBL25513571 | 0.83 | AKT1 (0.50) | AKT1BCHERXRAPPARGPPARD | |
| SCHEMBL6849624 | 0.78 | PKM (0.49) | AKT1COXFA4PKMCTSBKDM1A | |
| SCHEMBL16381660 | 0.76 | BCHE (0.40) | AKT1BCHEPPARGPPARAPDPK1 | |
| SCHEMBL14449323 | 0.76 | AKT1 (0.36) | AKT1RXRACOXFA4PKMKDM4E | |
| SCHEMBL25513573 | 0.75 | AKT1 (0.42) | AKT1BCHEPPARGPPARDPPARA | |
| SCHEMBL19030425 | 0.74 | AKT1 (0.41) | AKT1BCHEPPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083343-A1 | POLYCYCLIC COMPOUNDS AND METHODS THEREOF | HEPAITECH (BEIJING) BIOPHARMA TECHNOLOGY CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |