Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 4/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25513571 | 0.88 | AKT1 (0.50) | AKT1BCHEHTR1ASLC6A2HTR2C | |
| SCHEMBL25513581 | 0.86 | AKT1 (0.48) | AKT1BCHEPPARGPPARDPPARA | |
| SCHEMBL25513496 | 0.83 | HTR1A (0.37) | AKT1HTR1ASLC6A2HTR2CHTR2B | |
| SCHEMBL6849624 | 0.80 | PKM (0.49) | AKT1PKMNPC1MAPTRAB9A | |
| SCHEMBL15426955 | 0.79 | AKT1 (0.34) | AKT1HTR1ASLC6A2HTR2CHTR2B | |
| SCHEMBL25513573 | 0.79 | AKT1 (0.42) | AKT1BCHEHTR1ASLC6A2HTR2C | |
| SCHEMBL11256078 | 0.78 | SIGMAR1 (0.44) | AKT1BCHEHTR2CSIGMAR1PPARG | |
| SCHEMBL25513582 | 0.77 | AKT1 (0.40) | AKT1BCHEHTR1ASLC6A2HTR2C | |
| SCHEMBL14449323 | 0.77 | AKT1 (0.36) | AKT1PKMKDM4ERXRAHTT | |
| SCHEMBL14449820 | 0.75 | KDM4E (0.36) | AKT1PKMKDM4ERXRAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083343-A1 | POLYCYCLIC COMPOUNDS AND METHODS THEREOF | HEPAITECH (BEIJING) BIOPHARMA TECHNOLOGY CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |