Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25513571 | 0.91 | AKT1 (0.50) | AKT1BCHEKDM4ESIGMAR1PPARG | |
| SCHEMBL25513582 | 0.84 | AKT1 (0.40) | AKT1BCHEKDM4ESIGMAR1HTT | |
| SCHEMBL19954256 | 0.82 | SLC6A2 (0.35) | AKT1KDM4ESIGMAR1HTTATM | |
| SCHEMBL25513495 | 0.79 | AKT1 (0.46) | AKT1BCHEKDM4ESIGMAR1HTT | |
| SCHEMBL15280340 | 0.79 | PKM (0.41) | KDM4ESIGMAR1HTTATMALDH1A1 | |
| SCHEMBL25513581 | 0.75 | AKT1 (0.48) | AKT1BCHEKDM4EHTTATM | |
| SCHEMBL25513496 | 0.72 | HTR1A (0.37) | AKT1KDM4ESIGMAR1HTTATM | |
| SCHEMBL6849624 | 0.72 | PKM (0.49) | AKT1GAAPKM | |
| SCHEMBL10962460 | 0.71 | AKT1 (0.44) | AKT1BCHESIGMAR1PPARGPPARD | |
| SCHEMBL14449323 | 0.69 | AKT1 (0.36) | AKT1KDM4EHTTATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083343-A1 | POLYCYCLIC COMPOUNDS AND METHODS THEREOF | HEPAITECH (BEIJING) BIOPHARMA TECHNOLOGY CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |