Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.43 |
| ▸ | FABP3 | P05413 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991944 | 0.84 | KDM6B (0.51) | KDM4CKEAP1APEX1MPOALDH1A1 | |
| SCHEMBL25513516 | 0.83 | KDM4E (0.47) | KDM4CFERMT2ALDH1A1MAPTGAA | |
| SCHEMBL9223914 | 0.82 | KDM4C (0.53) | KDM4CAPEX1ALDH1A1MAPTKMT2A | |
| SCHEMBL15636197 | 0.81 | KDM6B (0.54) | KDM4CKEAP1APEX1CDK2KDM4E | |
| SCHEMBL15635498 | 0.81 | MPO (0.49) | KDM4CKEAP1APEX1MPOALDH1A1 | |
| SCHEMBL6681562 | 0.80 | APEX1 (0.44) | KDM4CKEAP1APEX1MPOALDH1A1 | |
| SCHEMBL16168119 | 0.80 | KEAP1 (0.49) | KEAP1APEX1MPOALDH1A1MAPT | |
| SCHEMBL13073780 | 0.80 | ALDH1A1 (0.49) | KEAP1APEX1MPOALDH1A1MAPT | |
| SCHEMBL19980681 | 0.79 | KEAP1 (0.60) | KEAP1MPOALDH1A1MAPTGAA | |
| SCHEMBL15635133 | 0.79 | MPO (0.47) | KDM4CKEAP1APEX1MPOALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078426-A1 | COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USE THEREOF | 上海优理惠生医药有限公司 | 2023-05-11 | — | — | WO | disclosed |