Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | VHL | P40337 | 1/20 | 0.41 |
| ▸ | ELOC | Q15369 | 1/20 | 0.41 |
| ▸ | ELOB | Q15370 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17083596 | 0.79 | ALOX15 (0.44) | ALOX15NAMPTKDM4ENPC1ALDH1A1 | |
| SCHEMBL2760780 | 0.78 | NPC1 (0.43) | ALOX15VHLELOCELOBNAMPT | |
| SCHEMBL25725671 | 0.76 | ALOX15 (0.41) | ALOX15NAMPT | |
| SCHEMBL26203744 | 0.75 | ALOX15 (0.40) | ALOX15NAMPTTSHRALDH1A1 | |
| SCHEMBL25516080 | 0.72 | TAAR1 (0.46) | — | |
| SCHEMBL276216 | 0.71 | ALOX15 (0.50) | ALOX15TYRNAMPTKDM4ENPC1 | |
| SCHEMBL25515787 | 0.71 | ALOX15 (0.44) | ALOX15VHLELOCELOBTSHR | |
| SCHEMBL12381495 | 0.68 | TBXAS1 (0.56) | VHLELOCELOBTYRNAMPT | |
| SCHEMBL7169389 | 0.68 | TYR (0.37) | VHLELOCELOBTYR | |
| SCHEMBL24097278 | 0.67 | ALOX15 (0.50) | ALOX15NAMPTKDM4ENPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081306-A1 | INDOLIZINE COMPOUNDS FOR THE TREATMENT OF MENTAL DISORDERS OR MENTAL ENHANCEMENT | TACTOGEN INC (US) | 2023-05-11 | — | — | WO | disclosed |