Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | VHL | P40337 | 1/20 | 0.36 |
| ▸ | ELOC | Q15369 | 1/20 | 0.36 |
| ▸ | ELOB | Q15370 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23122613 | 0.79 | ALOX15 (0.44) | ALOX15ENPP2CHRNA7 | |
| SCHEMBL25218446 | 0.79 | ALOX15 (0.44) | ALOX15TSHRCHRNA7KDM4ENPC1 | |
| SCHEMBL25269278 | 0.79 | ALOX15 (0.44) | ALOX15TSHRCHRNA7KDM4ENPC1 | |
| SCHEMBL2760780 | 0.78 | NPC1 (0.43) | ALOX15VHLELOCELOBTSHR | |
| SCHEMBL28042211 | 0.77 | AKR1B1 (0.45) | ALOX15TSHRTBXAS1KDM4EALDH1A1 | |
| SCHEMBL22401897 | 0.75 | ALOX15 (0.40) | ALOX15CHRNA7 | |
| SCHEMBL25516122 | 0.72 | PNMT (0.47) | — | |
| SCHEMBL25515767 | 0.71 | ALOX15 (0.44) | ALOX15VHLELOCELOBTSHR | |
| SCHEMBL24339261 | 0.71 | TBXAS1 (0.57) | CYP11B1CYP11B2PRKCIRECQLTBXAS1 | |
| SCHEMBL18727799 | 0.71 | CHRNA7 (0.34) | CHRNA7ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081306-A1 | INDOLIZINE COMPOUNDS FOR THE TREATMENT OF MENTAL DISORDERS OR MENTAL ENHANCEMENT | TACTOGEN INC (US) | 2023-05-11 | — | — | WO | disclosed |