SCHEMBL25515946

SCHEMBL25515946

CC1C=Cc2cccc(-c3cc(N)cc(-c4ccccc4)c3)c2C1

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.36
HTR1A P08908 4/20 0.33
HTR7 P34969 4/20 0.33
BRD4 O60885 1/20 0.32
CREBBP Q92793 1/20 0.32
ANPEP P15144 1/20 0.30
IL1RN P18510 1/20 0.30
ERAP2 Q6P179 1/20 0.30
ERAP1 Q9NZ08 1/20 0.30
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24022972 0.81 MAOA (0.37) MAOAHTR1AHTR7
SCHEMBL24154513 0.73 HTR1A (0.34) HTR1AHTR7
SCHEMBL20751756 0.71 CD44 (0.33) SLC6A2SLC6A4SLC6A3
SCHEMBL27462240 0.70 HTR1A (0.42) HTR1AHTR7BRD4CREBBPSLC6A2
SCHEMBL24315218 0.69 KDM4E (0.31) HTR1AHTR7SLC6A2SLC6A4SLC6A3
SCHEMBL27479194 0.68 HTR1A (0.41) HTR1AHTR7BRD4CREBBPSLC6A2
SCHEMBL27477090 0.68 HTR1A (0.41) HTR1AHTR7BRD4CREBBPSLC6A2
SCHEMBL19752161 0.67 CA12 (0.49) MAOA
SCHEMBL15837471 0.66 MAOA (0.67) MAOA
SCHEMBL4267156 0.66 MAOA (0.67) MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4186959-A1 COMPOSITION, LIGHT-EMITTING DEVICE, ELECTRONIC APPARATUS, CONSUMER PRODUCT, AND ORGANOMETALLIC COMPOUND Samsung Display Co., Ltd. (KR) 2023-05-31 EP disclosed