SCHEMBL25516768

SCHEMBL25516768

c1ccc2c(c1)ccc1oc3c(N(c4ccc5c(c4)oc4ccccc45)c4ccc5sc6ccccc6c5c4)cccc3c12

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
DUSP3 P51452 1/20 0.31
AHR P35869 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25516518 0.96 TDP1 (0.34) TDP1L3MBTL1DUSP3AHRESR2
SCHEMBL25873435 0.93 ALDH1A1 (0.33) TDP1L3MBTL1AHRESR2
SCHEMBL24887418 0.91 IKBKB (0.32) TDP1L3MBTL1DUSP3AHRESR2
SCHEMBL25516106 0.90 TDP1 (0.38) TDP1L3MBTL1DUSP3AHR
SCHEMBL24657716 0.89 TDP1 (0.34) TDP1L3MBTL1DUSP3AHR
SCHEMBL25886172 0.88 TDP1 (0.34) TDP1L3MBTL1DUSP3AHRESR2
SCHEMBL21398885 0.87 NPC1 (0.34) AHRESR2
SCHEMBL17382956 0.87 ABCG2 (0.36) TDP1AHR
SCHEMBL24887197 0.87 DUSP3 (0.33) DUSP3AHR
SCHEMBL25873448 0.86 AHR (0.33) TDP1L3MBTL1AHRESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240215441-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2024-06-27 US disclosed
WO-2023132694-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2023-07-13 WO disclosed
WO-2023085881-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240215441-A1 ORGANIC LIGHT EMITTING DEVICE CRY2, CRY1, AHR TDP1 3725/4885L3MBTL1 730/4885DUSP3 4437/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.