SCHEMBL25516983

SCHEMBL25516983

CNC(=O)[C@@H](N)CCCCN=[N+]=[N-]

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NOS2 P35228 5/20 0.39
▸ NOS1 P29475 4/20 0.39
▸ NOS3 P29474 3/20 0.39
▸ CYP1A2 P05177 1/20 0.39
▸ CYP3A4 P08684 1/20 0.39
▸ TSHR P16473 1/20 0.39
▸ BLM P54132 1/20 0.38
▸ DPP7 Q9UHL4 3/20 0.37
▸ SLC15A1 P46059 1/20 0.37
▸ GNAI3 P08754 1/20 0.36
▸ GNAO1 P09471 1/20 0.36
▸ GNAI1 P63096 1/20 0.36
▸ CHRM2 P08172 1/20 0.35
▸ CHRM4 P08173 1/20 0.35
▸ CHRM1 P11229 1/20 0.35
▸ DPP8 Q6V1X1 2/20 0.34
▸ DPP9 Q86TI2 2/20 0.34
▸ DDAH1 O94760 1/20 0.34
▸ DPP4 P27487 1/20 0.34
▸ MEN1 O00255 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13446011 0.81 DPP7 (0.43) NOS1DPP7SLC15A1GNAI3GNAO1
SCHEMBL17274222 0.79 — —
SCHEMBL14031296 0.79 NOS2 (0.56) NOS2NOS1NOS3CYP1A2CYP3A4
SCHEMBL29588594 0.79 NOS2 (0.56) NOS2NOS1NOS3CYP1A2CYP3A4
SCHEMBL14439654 0.79 NOS2 (0.56) NOS2NOS1NOS3CYP1A2CYP3A4
SCHEMBL15888955 0.79 NOS2 (0.43) NOS2NOS1NOS3CYP1A2CYP3A4
SCHEMBL13539965 0.78 NOS1 (0.40) NOS2NOS1NOS3CYP1A2CYP3A4
SCHEMBL8403553 0.78 DPP7 (0.48) DPP7SLC15A1GNAI3GNAO1GNAI1
SCHEMBL23586514 0.77 NOS2 (0.57) NOS2NOS1NOS3CYP1A2CYP3A4
Hydrochloric Acid SCHEMBL21802128 0.77 NOS2 (0.57) NOS2NOS1NOS3CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230158155-A1 Cell Surface Receptor Binding Compounds and Conjugates LYCIA THERAPEUTICS, INC. 2023-05-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230158155-A1 Cell Surface Receptor Binding Compounds and Conjugates M6PR, ASGR1, IGF2R NOS2 4668/4885NOS1 4619/4885NOS3 4665/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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