SCHEMBL25517569

SCHEMBL25517569

COc1cc(C)ccc1OCCN

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 12/20 0.65
MAPT P10636 10/20 0.65
HPGD P15428 5/20 0.65
CYP2C9 P11712 3/20 0.65
CYP2C19 P33261 3/20 0.65
POLB P06746 3/20 0.65
ALDH1A1 P00352 3/20 0.65
MAPK1 P28482 2/20 0.65
MEN1 O00255 1/20 0.65
USP2 O75604 1/20 0.65
ALOX12 P18054 1/20 0.65
KMT2A Q03164 1/20 0.65
NPSR1 Q6W5P4 1/20 0.65
L3MBTL4 Q8NA19 1/20 0.61
L3MBTL3 Q96JM7 1/20 0.61
ACHE P22303 1/20 0.61
RAB9A P51151 4/20 0.59
NPC1 O15118 3/20 0.59
SMN1; SMN2 Q16637 4/20 0.58
KDM4E B2RXH2 3/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15595696 0.85 L3MBTL1 (0.65) L3MBTL1MAPTHPGDCYP2C9CYP2C19
SCHEMBL13631020 0.84 ACHE (0.59) L3MBTL1MAPTHPGDCYP2C9CYP2C19
SCHEMBL10196613 0.83 L3MBTL1 (0.67) L3MBTL1MAPTHPGDCYP2C9CYP2C19
SCHEMBL8256686 0.83 L3MBTL1 (0.72) L3MBTL1MAPTHPGDCYP2C9CYP2C19
SCHEMBL8234577 0.81 L3MBTL1 (0.65) L3MBTL1MAPTHPGDCYP2C9CYP2C19
SCHEMBL11890493 0.81 L3MBTL4 (0.66) L3MBTL1MAPTHPGDCYP2C9CYP2C19
SCHEMBL10107391 0.81 L3MBTL1 (0.70) L3MBTL1MAPTHPGDCYP2C9CYP2C19
SCHEMBL18924248 0.81 MAPT (0.59) L3MBTL1MAPTHPGDCYP2C9CYP2C19
SCHEMBL3373256 0.81 L3MBTL1 (0.67) L3MBTL1MAPTHPGDCYP2C9CYP2C19
SCHEMBL1998887 0.81 L3MBTL1 (0.65) L3MBTL1MAPTHPGDCYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230157996-A1 SMALL-MOLECULE INHIBITOR TARGETING EB VIRUS NUCLEAR ANTIGEN PROTEIN, PREPARATION METHOD AND USE THEREOF Shenzhen Bay Laboratory (CN) 2023-05-25 US disclosed
US-20230157996-A1 SMALL-MOLECULE INHIBITOR TARGETING EB VIRUS NUCLEAR ANTIGEN PROTEIN, PREPARATION METHOD AND USE THEREOF Shenzhen Bay Laboratory (CN) 2023-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230157996-A1 SMALL-MOLECULE INHIBITOR TARGETING EB VIRUS NUCLEAR ANTIGEN PROTEIN, PREPARATION METHOD AND USE THEREOF SSB, EBNA1BP2, PML L3MBTL1 2434/4885MAPT 2170/4885HPGD 4591/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.