SCHEMBL25517652

SCHEMBL25517652

Cc1ccc2c(c1)oc1c(-c3ccccn3)c(C)ccc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 6/20 0.52
KDM4E B2RXH2 5/20 0.52
HPGD P15428 5/20 0.52
PKM P14618 5/20 0.52
RAB9A P51151 5/20 0.52
TP53 P04637 5/20 0.52
HSD17B10 Q99714 4/20 0.52
ALDH1A1 P00352 4/20 0.52
SMN1; SMN2 Q16637 3/20 0.52
HTT P42858 2/20 0.39
METAP1 P53582 2/20 0.39
METAP2 P50579 1/20 0.39
CBFB Q13951 1/20 0.39
NPSR1 Q6W5P4 2/20 0.38
TSHR P16473 2/20 0.38
KCNA3 P22001 1/20 0.38
GRM5 P41594 1/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
CYP1A2 P05177 4/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16716066 0.87 PGR (0.45) NPC1KDM4EHPGDPKMRAB9A
SCHEMBL19258076 0.83 CCR1 (0.42) NPC1KDM4EHPGDPKMRAB9A
SCHEMBL19431890 0.83 TDO2 (0.40) NPC1KDM4EHPGDPKMRAB9A
SCHEMBL26083472 0.82 NPC1 (0.51) NPC1KDM4EHPGDPKMRAB9A
SCHEMBL18790947 0.80 CBFB (0.39) NPC1KDM4EHPGDPKMRAB9A
SCHEMBL18790946 0.79 CYP2A6 (0.37) NPC1KDM4EHPGDPKMRAB9A
SCHEMBL19723336 0.79 TDO2 (0.42) NPC1KDM4EHPGDPKMRAB9A
SCHEMBL19507370 0.78 MAOB (0.41) NPC1KDM4EHPGDPKMRAB9A
SCHEMBL17759087 0.77 NPC1 (0.39) NPC1KDM4EHPGDPKMRAB9A
SCHEMBL20258129 0.77 PGR (0.42) NPC1KDM4EHPGDRAB9ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230144101-A1 LIGHT-EMITTING MATERIAL WITH A POLYCYCLIC LIGAND Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230144101-A1 LIGHT-EMITTING MATERIAL WITH A POLYCYCLIC LIGAND TRPC4, CRY1, TRPC1 NPC1 3269/4885KDM4E 1963/4885HPGD 3280/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.