Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19627549 | 0.83 | ALDH1A1 (0.37) | MAPTALDH1A1HPGDKDM4EGAA | |
| SCHEMBL3968110 | 0.79 | ALDH1A1 (0.48) | MAPTALDH1A1HPGDKDM4EGAA | |
| SCHEMBL16310081 | 0.78 | ALDH1A1 (0.33) | ALDH1A1CYP1A2MCL1CYP1A1CYP1B1 | |
| SCHEMBL20684520 | 0.74 | MAOA (0.34) | ALDH1A1KDM4EPOLB | |
| SCHEMBL27293211 | 0.73 | ALDH1A1 (0.43) | MAPTALDH1A1HPGDKDM4ETSHR | |
| SCHEMBL87447 | 0.73 | ALOX5 (0.47) | MAPTALDH1A1HPGDKDM4EGAA | |
| SCHEMBL29392003 | 0.73 | ALOX5 (0.47) | MAPTALDH1A1HPGDKDM4EGAA | |
| SCHEMBL8442226 | 0.72 | MAPT (0.50) | MAPTALDH1A1HPGDKDM4EGAA | |
| SCHEMBL41439 | 0.71 | TDP1 (0.46) | MAPTALDH1A1KDM4ETSHRRAB9A | |
| SCHEMBL29651844 | 0.71 | TDP1 (0.46) | MAPTALDH1A1KDM4ETSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4393924-A1 | IMIDAZO [1,2-A] PYRAZINE OR PYRAZOLO [1,5-A] PYRIMIDINE DERIVATIVE AND USE THEREOF | Tencent Technology (Shenzhen) Company Limited (CN) | 2024-07-03 | — | — | EP | disclosed |
| EP-3728280-B1 | METHOD FOR IMPROVING THE ORAL BIOAVAILABILITY OF A DRUG | PHARMACYTICS B V (NL) | 2023-06-28 | — | — | EP | disclosed |