Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 4/20 | 0.33 |
| ▸ | EPHA2 | P29317 | 3/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.32 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22847754 | 0.79 | HRH3 (0.44) | HRH3SLC6A2PRMT5WDR77 | |
| SCHEMBL218065 | 0.75 | SMN1; SMN2 (0.40) | — | |
| SCHEMBL3436781 | 0.73 | PDK1 (0.56) | HRH3SLC6A2PDK1EPHA2KDR | |
| SCHEMBL12210937 | 0.73 | PDK1 (0.56) | HRH3SLC6A2PDK1EPHA2KDR | |
| SCHEMBL7925158 | 0.73 | PDK1 (0.56) | HRH3SLC6A2PDK1EPHA2KDR | |
| SCHEMBL18773644 | 0.72 | HRH3 (0.46) | HRH3SLC6A2IRAK4PDK1EPHA2 | |
| SCHEMBL25670134 | 0.72 | HRH3 (0.46) | HRH3SLC6A2IRAK4PDK1EPHA2 | |
| SCHEMBL25670128 | 0.72 | HRH3 (0.46) | HRH3SLC6A2IRAK4PDK1EPHA2 | |
| SCHEMBL15732028 | 0.72 | HRH3 (0.46) | HRH3SLC6A2IRAK4PDK1EPHA2 | |
| SCHEMBL15727444 | 0.70 | PDK1 (0.58) | HRH3SLC6A2IRAK4PDK1EPHA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230148436-A2 | NOVEL SMALL MOLECULE IMMUNE AGONISTS AND IMMUNE TARGETING COMPOUNDS AND APPLICATION THEREOF | SHENZHEN UNIVERSITY (CN) | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230148436-A2 | NOVEL SMALL MOLECULE IMMUNE AGONISTS AND IMMUNE TARGETING COMPOUNDS AND APPLICATION THEREOF | IFNG, IFNAR1, STING1 | HRH3 253/4885SLC6A2 4323/4885PRMT5 3953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.