Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25521022 | 0.94 | CYSLTR2 (0.46) | CYP1A2CYP2C9CYP2C19CYSLTR2CYSLTR1 | |
| SCHEMBL4688464 | 0.92 | CYSLTR2 (0.47) | CYP1A2CYP2C9CYP2C19CYSLTR2CYSLTR1 | |
| SCHEMBL20711188 | 0.92 | CYSLTR2 (0.47) | CYP1A2CYP2C9CYP2C19CYSLTR2CYSLTR1 | |
| SCHEMBL20711189 | 0.92 | CYP1A2 (0.42) | CYP1A2CYP2C9CYP2C19CYSLTR2CYSLTR1 | |
| SCHEMBL28110318 | 0.92 | CYSLTR2 (0.47) | CYP1A2CYP2C9CYP2C19CYSLTR2CYSLTR1 | |
| SCHEMBL11350827 | 0.92 | CYSLTR2 (0.47) | CYP1A2CYP2C9CYP2C19CYSLTR2CYSLTR1 | |
| SCHEMBL5875326 | 0.92 | CYSLTR2 (0.47) | CYP1A2CYP2C9CYP2C19CYSLTR2CYSLTR1 | |
| Water SCHEMBL7553028 | 0.91 | CYSLTR2 (0.46) | CYP1A2CYP2C9CYP2C19CYSLTR2CYSLTR1 | |
| SCHEMBL14747967 | 0.91 | CYSLTR2 (0.42) | CYP1A2CYP2C9CYP2C19CYSLTR2CYSLTR1 | |
| SCHEMBL25475053 | 0.89 | CYSLTR2 (0.44) | CYP1A2CYP2C9CYP2C19CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159569-A1 | DUAL HDAC6/PROTEASOME INHIBITORS, AND METHODS OF USE THEREOF | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2023-05-25 | — | — | US | disclosed |
| CN-109384981-A | Modified conjugated diene rubber composition and tire | 旭化成株式会社 | 2019-02-26 | — | — | CN | disclosed |
| CN-109384982-A | Modified conjugated diene polymer composition and tire | 旭化成株式会社 | 2019-02-26 | — | — | CN | disclosed |
| CN-108164645-A | MODIFIED CONJUGATED DIENE POLYMER, MODIFIED CONJUGATED DIENE POLYMER COMPOSITION AND TIRE | 旭化成株式会社 | 2018-06-15 | — | — | CN | disclosed |
| CN-107250172-A | Modified conjugated diene polymer and its manufacture method and modified conjugated diene polymer composition | 旭化成株式会社 | 2017-10-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159569-A1 | DUAL HDAC6/PROTEASOME INHIBITORS, AND METHODS OF USE THEREOF | HDAC6, PSMG3, PSMB2 | CYP1A2 4623/4885CYP2C9 4849/4885CYP2C19 4808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.