Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.54 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.53 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.51 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979115 | 0.90 | NR1H4 (0.51) | MAPTCYP2C19CYP1A2CYP2C9POLB | |
| SCHEMBL13129153 | 0.85 | LTC4S (0.68) | MAPTCYP2C19CYP1A2CYP2C9POLB | |
| SCHEMBL7606676 | 0.83 | MAPT (0.67) | MAPTCYP2C19CYP1A2CYP2C9POLB | |
| SCHEMBL23635268 | 0.82 | KDM4E (0.57) | MAPTCYP2C19CYP1A2CYP2C9POLB | |
| SCHEMBL3428272 | 0.81 | TSHR (0.48) | MAPTCYP2C9POLBHPGDALDH1A1 | |
| SCHEMBL9372689 | 0.78 | NPC1 (0.60) | MAPTPOLBHPGDALDH1A1MEN1 | |
| SCHEMBL8820818 | 0.77 | MAPT (0.71) | MAPTCYP2C19CYP1A2CYP2C9POLB | |
| SCHEMBL9979383 | 0.77 | MEN1 (0.44) | MAPTCYP2C19CYP1A2ALDH1A1GPR174 | |
| SCHEMBL14900902 | 0.77 | POLB (0.72) | MAPTCYP2C19CYP1A2CYP2C9POLB | |
| SCHEMBL11133861 | 0.76 | ESR1 (0.51) | MAPTCYP2C19CYP1A2CYP2C9POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11649475-B2 | Dioxetane compounds and their use for the detection of microorganisms | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2023-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11649475-B2 | Dioxetane compounds and their use for the detection of microorganisms | DAXX, LITAF, EDF1 | MAPT 4026/4885CYP2C19 662/4885CYP1A2 208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.