Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.56 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | CFD | P00746 | 1/20 | 0.49 |
| ▸ | F11 | P03951 | 1/20 | 0.49 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13129153 | 0.88 | LTC4S (0.68) | MAPTCYP2C19CYP1A2CYP2C9POLB | |
| SCHEMBL25518944 | 0.83 | MAPT (0.59) | MAPTCYP2C19CYP1A2CYP2C9POLB | |
| SCHEMBL28787280 | 0.82 | LTC4S (0.54) | MAPTCYP2C19CYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL1548172 | 0.80 | MAPT (1.00) | MAPTCYP2C19CYP1A2CYP2C9POLB | |
| SCHEMBL8820818 | 0.80 | MAPT (0.71) | MAPTCYP2C19CYP1A2CYP2C9POLB | |
| SCHEMBL620069 | 0.79 | RAB9A (0.53) | MAPTCYP2C19CYP1A2POLBALDH1A1 | |
| SCHEMBL14900902 | 0.79 | POLB (0.72) | MAPTCYP2C19CYP1A2CYP2C9POLB | |
| SCHEMBL30739671 | 0.78 | MAPT (0.69) | MAPTCYP2C19CYP1A2CYP2C9POLB | |
| SCHEMBL30798823 | 0.78 | MAPT (0.69) | MAPTCYP2C19CYP1A2CYP2C9POLB | |
| SCHEMBL7890737 | 0.78 | MAPT (0.69) | MAPTCYP2C19CYP1A2CYP2C9POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020032238-A1 | Biphenylcarboxylic acid amides, the preparation thereof and the use thereof as medicaments | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020032238-A1 | Biphenylcarboxylic acid amides, the preparation thereof and the use thereof as medicaments | MTTP, CETP, FABP1 | MAPT 4022/4885CYP2C19 200/4885CYP1A2 84/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.