Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | WRN | Q14191 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7338739 | 0.82 | NAAA (0.40) | ALDH1A1CYP1A2CYP2C19HPGDBLM | |
| SCHEMBL22204635 | 0.79 | ALDH1A1 (0.35) | ALDH1A1CYP1A2CYP2C19HPGDBLM | |
| SCHEMBL11964190 | 0.78 | NAAA (0.38) | ALDH1A1CYP1A2CYP2C19HPGDBLM | |
| SCHEMBL681192 | 0.78 | NAAA (0.52) | ALDH1A1CYP1A2CYP2C19HPGDBLM | |
| SCHEMBL36821 | 0.77 | — | — | |
| Methane SCHEMBL6300031 | 0.75 | NAAA (0.50) | ALDH1A1CYP1A2CYP2C19HPGDBLM | |
| Methane SCHEMBL21632462 | 0.75 | CYP4F2 (0.44) | ALDH1A1CYP1A2GAAKDM4ETRPA1 | |
| SCHEMBL29958613 | 0.75 | CYP4F2 (0.44) | ALDH1A1CYP1A2GAAKDM4ETRPA1 | |
| SCHEMBL36866 | 0.74 | POLB (0.41) | ALDH1A1CYP2C19GAA | |
| SCHEMBL10033490 | 0.74 | TSHR (0.42) | ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2558538-A2 | HIGH MOLECULAR WEIGHT ZWITTERION-CONTAINING POLYMERS | Oligasis (US) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011130694-A2 | HIGH MOLECULAR WEIGHT ZWITTERION-CONTAINING POLYMERS | OLIGASIS (US) | 2011-10-20 | — | — | WO | disclosed |