SCHEMBL25519822

SCHEMBL25519822

CC(C)/C=C/c1c(F)cc(F)cc1F

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.30
ALOX15 P16050 1/20 0.30
ALOX12 P18054 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18243049 0.76 ERN1 (0.31)
SCHEMBL9967780 0.74 PTGS1 (0.47) ALOX5
SCHEMBL3193831 0.73 ERN1 (0.32)
SCHEMBL15145958 0.73 ERN1 (0.32)
SCHEMBL9967725 0.72 NFE2L2 (0.55)
SCHEMBL21766556 0.70 VCP (0.36)
SCHEMBL24434471 0.70
SCHEMBL5539447 0.69 ERN1 (0.32)
SCHEMBL5539442 0.69 ERN1 (0.32)
SCHEMBL1673714 0.68 NQO2 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023086428-A2 NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) 2023-05-19 WO disclosed