Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | TBK1 | Q9UHD2 | 15/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.36 |
| ▸ | IKBKE | Q14164 | 6/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25208044 | 0.87 | MBOAT4 (0.38) | CNR2CNR1LRRK2 | |
| SCHEMBL30397961 | 0.81 | TBK1 (0.33) | CNR2CNR1TBK1 | |
| SCHEMBL25228679 | 0.81 | TBK1 (0.33) | CNR2CNR1TBK1 | |
| SCHEMBL31444321 | 0.79 | LRRK2 (0.32) | CNR2CNR1LRRK2 | |
| SCHEMBL25207890 | 0.77 | SYK (0.43) | CNR2LRRK2 | |
| SCHEMBL14805373 | 0.76 | CNR1 (0.43) | CNR2CNR1TBK1LRRK2IKBKE | |
| SCHEMBL25520567 | 0.74 | LRRK2 (0.53) | LRRK2 | |
| SCHEMBL25204937 | 0.74 | KDM4E (0.45) | — | |
| SCHEMBL25206289 | 0.74 | MBOAT4 (0.30) | — | |
| SCHEMBL29631720 | 0.73 | PTGS2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091726-A1 | INHIBITORS OF CYCLIN‑DEPENDENT KINASE 12 (CDK12) | SYROS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |