⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25520858 | 0.93 | — | — | |
| SCHEMBL25520824 | 0.79 | HTR2A (0.33) | — | |
| SCHEMBL25520841 | 0.78 | NR3C1 (0.32) | — | |
| SCHEMBL25520840 | 0.78 | NR3C1 (0.32) | — | |
| SCHEMBL25520803 | 0.75 | PSMB1 (0.31) | — | |
| SCHEMBL25520862 | 0.74 | — | — | |
| SCHEMBL25520741 | 0.74 | HTR2C (0.41) | — | |
| SCHEMBL25520795 | 0.72 | — | — | |
| SCHEMBL25520805 | 0.72 | HTR2C (0.30) | — | |
| SCHEMBL25520837 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159456-A1 | N-SUBSTITUTED INDOLES | TERRAN BIOSCIENCES INC (US) | 2023-05-25 | — | — | US | disclosed |
| US-20230159456-A1 | N-SUBSTITUTED INDOLES | TERRAN BIOSCIENCES INC (US) | 2023-05-25 | — | — | US | disclosed |
| WO-2023077127-A2 | N-SUBSTITUTED INDOLES | TERRAN BIOSCIENCES, INC. (US) | 2023-05-04 | — | — | WO | disclosed |