SCHEMBL25520840

SCHEMBL25520840

CN(C)C(C)(C)Cn1ccc2c3c(ccc21)CCCC3

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 2/20 0.32
HTR6 P50406 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25520841 0.97 NR3C1 (0.32) NR3C1HTR6
SCHEMBL25520803 0.81 PSMB1 (0.31)
SCHEMBL25520853 0.80
SCHEMBL25520741 0.80 HTR2C (0.41) HTR6
SCHEMBL25520862 0.80
SCHEMBL25520857 0.78
SCHEMBL25520805 0.77 HTR2C (0.30)
SCHEMBL25520743 0.76 HTR2C (0.33) NR3C1
SCHEMBL25520812 0.76
SCHEMBL25520831 0.76 HTR2C (0.37) HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159456-A1 N-SUBSTITUTED INDOLES TERRAN BIOSCIENCES INC (US) 2023-05-25 US disclosed
US-20230159456-A1 N-SUBSTITUTED INDOLES TERRAN BIOSCIENCES INC (US) 2023-05-25 US disclosed
WO-2023077127-A2 N-SUBSTITUTED INDOLES TERRAN BIOSCIENCES, INC. (US) 2023-05-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159456-A1 N-SUBSTITUTED INDOLES TPH2, TPH1, AANAT NR3C1 409/4885HTR6 10/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.