Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.40 |
| ▸ | MTOR | P42345 | 2/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | CAMKK1 | Q8N5S9 | 2/20 | 0.38 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.36 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
| ▸ | PI4KA | P42356 | 1/20 | 0.35 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25521680 | 0.82 | ADORA2A (0.54) | ADORA2AGRM4PIK3CDPIK3CAPIK3CB | |
| SCHEMBL25524007 | 0.77 | PDGFRB (0.40) | PIK3CDPIK3CAPIK3CBMTORPIK3CG | |
| SCHEMBL25521916 | 0.75 | ERN1 (0.46) | AAK1ERN1 | |
| SCHEMBL25524104 | 0.74 | PDGFRB (0.51) | PIK3CDPIK3CAHTTNPC1MAPT | |
| SCHEMBL25522059 | 0.74 | MAP4K4 (0.54) | — | |
| SCHEMBL25524008 | 0.74 | ACHE (0.56) | ADORA2ANPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL23496977 | 0.73 | ADORA2A (0.57) | ADORA2AGRM4PIK3CDPIK3CAPIK3CB | |
| SCHEMBL30719601 | 0.73 | ADORA2A (0.57) | ADORA2AGRM4PIK3CDPIK3CAPIK3CB | |
| SCHEMBL25522194 | 0.72 | AR (0.50) | NPC1MAPTRAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL6371765 | 0.72 | PI4KA (0.52) | ADORA2APDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086428-A2 | NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |