Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.34 |
| ▸ | F2RL1 | P55085 | 3/20 | 0.34 |
| ▸ | VRK1 | Q99986 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.32 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25522339 | 0.81 | KDM4E (0.40) | KDM4EGRIN2B | |
| SCHEMBL25522207 | 0.78 | ABCG2 (0.40) | KDM4EGRIN2BVRK1ABCG2ESR1 | |
| SCHEMBL25522347 | 0.78 | KDM4E (0.48) | KDM4E | |
| SCHEMBL25521675 | 0.77 | ABCG2 (0.42) | KDM4EGRIN2BVRK1ABCG2ESR2 | |
| SCHEMBL25524102 | 0.74 | ABCG2 (0.47) | KDM4EGRIN2BABCG2ESR1ESR2 | |
| SCHEMBL25522349 | 0.72 | ESR1 (0.36) | KDM4EESR1ESR2 | |
| SCHEMBL25522344 | 0.69 | CASR (0.36) | GCGR | |
| SCHEMBL25522343 | 0.69 | ESR1 (0.38) | KDM4EESR1ESR2GCGR | |
| SCHEMBL25522435 | 0.68 | RPS6KA3 (0.34) | JAK2JAK1TYK2KDRJAK3 | |
| SCHEMBL12483271 | 0.67 | ABCG2 (0.40) | KDM4EABCG2ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086428-A2 | NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |