Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 11/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | UBE2N | P61088 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | TET3 | O43151 | 1/20 | 0.38 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.38 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | KDM4B | O94953 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25522339 | 0.79 | KDM4E (0.40) | KDM4EL3MBTL1RAB9ANPC1 | |
| SCHEMBL25522334 | 0.78 | KDM4E (0.35) | KDM4E | |
| SCHEMBL25523414 | 0.77 | KDM4E (0.51) | KDM4EL3MBTL1RAB9ANPC1RAD52 | |
| SCHEMBL25522331 | 0.76 | L3MBTL1 (0.50) | KDM4EL3MBTL1RAB9ANPC1RAD52 | |
| SCHEMBL25522344 | 0.76 | CASR (0.36) | — | |
| SCHEMBL25522349 | 0.74 | ESR1 (0.36) | KDM4EL3MBTL1RAB9ANPC1 | |
| SCHEMBL25521795 | 0.73 | KDM4E (0.48) | KDM4EL3MBTL1RAB9ANPC1RAD52 | |
| SCHEMBL25522332 | 0.73 | ERN1 (0.43) | KDM4EL3MBTL1TRPV1 | |
| SCHEMBL1148845 | 0.72 | HRH1 (0.44) | TRPV1 | |
| SCHEMBL28275870 | 0.71 | L3MBTL1 (0.66) | KDM4EL3MBTL1RAB9ANPC1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086428-A2 | NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |