Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 2/20 | 0.36 |
| ▸ | GCGR | P47871 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.31 |
| ▸ | JUN | P05412 | 1/20 | 0.31 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.31 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25522217 | 0.77 | RPS6KA3 (0.35) | CASRGCGRHSD17B1HSD17B2 | |
| SCHEMBL25523412 | 0.76 | AHR (0.35) | CASRHSD17B1HSD17B2MEN1KMT2A | |
| SCHEMBL25522347 | 0.76 | KDM4E (0.48) | — | |
| SCHEMBL25522339 | 0.73 | KDM4E (0.40) | HSD17B1HSD17B2 | |
| SCHEMBL25521794 | 0.70 | KDM4E (0.39) | HSD17B1HSD17B2 | |
| SCHEMBL25522334 | 0.69 | KDM4E (0.35) | GCGR | |
| SCHEMBL25520946 | 0.68 | GABRA1 (0.44) | MEN1KMT2A | |
| SCHEMBL13614862 | 0.67 | PTPRC (0.40) | GCGRCD274 | |
| SCHEMBL7706281 | 0.65 | TAAR1 (0.38) | CASRCNR1CNR2JUNLTB4R | |
| SCHEMBL27822821 | 0.64 | KDM4E (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086428-A2 | NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |