Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.46 |
| ▸ | BRD1 | O95696 | 1/20 | 0.46 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.46 |
| ▸ | DAGLA | Q9Y4D2 | 11/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | GHSR | Q92847 | 2/20 | 0.42 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.41 |
| ▸ | PKLR | P30613 | 1/20 | 0.41 |
| ▸ | MLNR | O43193 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | DAGLB | Q8NCG7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25521770 | 0.76 | PKM (0.46) | PKMTRIM24BRD1BRPF1DAGLA | |
| SCHEMBL10154341 | 0.74 | PKM (0.66) | PKMTRIM24BRD1BRPF1DAGLA | |
| SCHEMBL22062310 | 0.72 | DAGLA (0.54) | PKMTRIM24BRD1BRPF1DAGLA | |
| SCHEMBL4521621 | 0.71 | PKM (0.58) | PKMTRIM24BRD1BRPF1DAGLA | |
| SCHEMBL2243703 | 0.70 | PKM (0.53) | PKMTRIM24BRD1BRPF1DAGLA | |
| SCHEMBL22062309 | 0.70 | PKM (0.53) | PKMTRIM24BRD1BRPF1DAGLA | |
| SCHEMBL8557904 | 0.69 | PKM (0.73) | PKMTRIM24BRD1BRPF1DAGLA | |
| SCHEMBL639690 | 0.69 | PKM (0.58) | PKMTRIM24BRD1BRPF1DAGLA | |
| SCHEMBL3776603 | 0.69 | PKM (0.58) | PKMTRIM24BRD1BRPF1DAGLA | |
| SCHEMBL30511906 | 0.69 | PKM (0.58) | PKMTRIM24BRD1BRPF1DAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083343-A1 | POLYCYCLIC COMPOUNDS AND METHODS THEREOF | HEPAITECH (BEIJING) BIOPHARMA TECHNOLOGY CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |