Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 4/20 | 0.73 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.65 |
| ▸ | BRD1 | O95696 | 1/20 | 0.65 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.65 |
| ▸ | GHSR | Q92847 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | MLNR | O43193 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | PKLR | P30613 | 2/20 | 0.51 |
| ▸ | DAGLA | Q9Y4D2 | 5/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557528 | 0.86 | PKM (0.71) | PKMTRIM24BRD1BRPF1GHSR | |
| SCHEMBL10154341 | 0.83 | PKM (0.66) | PKMTRIM24BRD1BRPF1GHSR | |
| SCHEMBL10239988 | 0.79 | PKM (0.67) | PKMTRIM24BRD1BRPF1GHSR | |
| SCHEMBL21857637 | 0.79 | PFKFB3 (0.58) | PKMTRIM24BRD1BRPF1GHSR | |
| SCHEMBL794002 | 0.79 | PKM (0.58) | PKMTRIM24BRD1BRPF1GHSR | |
| SCHEMBL22062310 | 0.78 | DAGLA (0.54) | PKMTRIM24BRD1BRPF1GHSR | |
| Hydrochloric Acid SCHEMBL9957679 | 0.78 | PKM (0.66) | PKMTRIM24BRD1BRPF1GHSR | |
| SCHEMBL639690 | 0.77 | PKM (0.58) | PKMTRIM24BRD1BRPF1GHSR | |
| SCHEMBL4521621 | 0.77 | PKM (0.58) | PKMTRIM24BRD1BRPF1GHSR | |
| SCHEMBL30511906 | 0.77 | PKM (0.58) | PKMTRIM24BRD1BRPF1GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1185153-A | Benzopyrans and pharmaceutical composition contg. same | CIBA GEIGY AG (CH) | 1998-06-17 | — | — | CN | disclosed |
| EP-0828733-A1 | BENZOPYRANS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Novartis AG (CH) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996037490-A1 | BENZOPYRANS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | NOVARTIS AG (CH) | 1996-11-28 | — | — | WO | disclosed |