Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | PTPRC | P08575 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL10567951 | 0.98 | FOLH1 (0.52) | FOLH1TP53HTTFFAR1FFAR4 | |
| SCHEMBL3995720 | 0.86 | TSHR (0.50) | TP53FFAR1FFAR4AKR1B1USP2 | |
| SCHEMBL4430140 | 0.86 | NPC1 (0.52) | FOLH1TP53HTTUSP2ALOX5 | |
| SCHEMBL1368181 | 0.85 | TP53 (0.63) | FOLH1TP53HTTNR4A2PTPRC | |
| SCHEMBL10689361 | 0.85 | FFAR1 (0.71) | FFAR1FFAR4AKR1B1 | |
| SCHEMBL5989548 | 0.85 | RXRA (0.59) | FOLH1TP53HTTFFAR1FFAR4 | |
| SCHEMBL11618778 | 0.84 | CFD (0.55) | FOLH1TP53HTTFFAR1NR4A2 | |
| SCHEMBL13870541 | 0.84 | FFAR1 (0.56) | FOLH1TP53HTTFFAR1FFAR4 | |
| SCHEMBL28141293 | 0.83 | AKR1B1 (0.58) | HTTFFAR1FFAR4AKR1B1PTPRC | |
| SCHEMBL11621301 | 0.83 | FFAR1 (0.60) | FFAR1FFAR4AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115385887-B | Method for preparing isoxadifen by catalyzing cyclization reaction through ammonium salt ionic liquid | 北京联本医药化学技术有限公司 | 2024-01-23 | — | — | CN | claimed |
| EP-2058294-B1 | METHOD FOR PRODUCING 2-(4-METHOXYCARBONYLMETHYLPHENOXYMETHYL)BENZOIC ACID METHYL ESTER | SUMITOMO CHEMICAL CO (JP) | 2013-01-02 | — | — | EP | claimed |
| WO-2011128911-A2 | IMPROVED PROCESS FOR LL-[(Z)-3-(DIMETHYLAMINO)PROPYIIDENEL-6-LL- DIHYDRODIBENZ[B,EL OXEPIN-2-ACETICACID | MSN LABORATORIES LIMITED (IN) | 2011-10-20 | — | — | WO | claimed |
| EP-2181989-A2 | Process for the preparation of olopatadine | Sumitomo Chemical Company, Limited (JP) | 2010-05-05 | — | — | EP | claimed |
| EP-2072507-A1 | TERTIARY ALKYL ESTER OF OXODIBENZOXEPIN ACETIC ACID | Sumitomo Chemical Company, Limited (JP) | 2009-06-24 | — | — | EP | claimed |
| EP-2058294-A1 | 2-(4-METHOXYCARBONYLMETHYLPHENOXYMETHYL)BENZOIC ACID METHYL ESTER AND METHOD FOR PRODUCING THE SAME | Sumitomo Chemical Company, Limited (JP) | 2009-05-13 | — | — | EP | claimed |
| EP-2004621-A2 | POLYMORPHIC FORMS OF OLOPATADINE HYDROCHLORIDE AND METHODS FOR PRODUCING OLOPATADINE AND SALTS THEREOF | Universität Zürich (CH) | 2008-12-24 | — | — | EP | claimed |
| WO-2007110761-A2 | POLYMORPHIC FORMS OF OLOPATADINE HYDROCHLORIDE AND METHODS FOR PRODUCING OLOPATADINE AND SALTS THEREOF | Universität Zürich (CH) | 2007-10-04 | — | — | WO | claimed |
| US-20070232814-A1 | Polymorphic forms of olopatadine hydrochloride and methods for producing olopatadine and salts thereof | UNIVERSITAT ZURICH (CH) | 2007-10-04 | — | — | US | claimed |
| CN-115385887-B | Method for preparing isoxadifen by catalyzing cyclization reaction through ammonium salt ionic liquid | 北京联本医药化学技术有限公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-115385887-B | Method for preparing isoxadifen by catalyzing cyclization reaction through ammonium salt ionic liquid | 北京联本医药化学技术有限公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-113620920-A | Preparation method of olopatadine hydrochloride | 四川子仁制药有限公司 | 2021-11-09 | — | — | CN | disclosed |
| CN-102838582-B | Preparation method of isoxepac | HUZHOU HENGYUAN BIOCHEM TECHNOLOGY CO LTD | 2014-03-26 | — | — | CN | disclosed |
| EP-2181989-B1 | Process for the preparation of olopatadine | SUMITOMO CHEMICAL CO (JP) | 2013-05-22 | — | — | EP | disclosed |
| US-4816591-A | 6,11-dihydrodibenz[b,e]oxepin-acetic acids and derivatives | AMERICAN HOECHST CORPORATION (US) | 1989-03-28 | — | — | US | disclosed |
| EP-0069810-B1 | NOVEL DIBENZOXEPINS, THEIR PREPARATION, COMPOSITIONS CONTAINING THEM AND THE USE OF DIBENZOXEPINS IN THE TREATMENT OF ALLERGIC CONDITIONS | MERCK & CO. INC. (US) | 1986-12-03 | — | — | EP | disclosed |
| US-4585788-A | 6,11-dihydrodibenz[b,e]oxepin-acetic acids and derivatives | AMERICAN HOECHST CORPORATION (US) | 1986-04-29 | — | — | US | disclosed |
| EP-0069810-A1 | Novel dibenzoxepins, their preparation, compositions containing them and the use of dibenzoxepins in the treatment of allergic conditions | MERCK & CO. INC. (US) | 1983-01-19 | — | — | EP | disclosed |
| US-4282365-A | Dibenz[b,e]oxepin compounds | MERCK & CO., INC. (US) | 1981-08-04 | — | — | US | disclosed |
| US-4082850-A | TOPICAL APPLICATION OF A 6,11-DIHYDROBENZ(B,E)OXEPIN-ALKANOIC ACID OR DERIVATIVES THEREOF | AMERICAN HOECHST CORPORATION (US) | 1978-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232814-A1 | Polymorphic forms of olopatadine hydrochloride and methods for producing olopatadine and salts thereof | HRH4, HRH1, HRH3 | FOLH1 3493/4885TP53 2526/4885HTT 1020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.