Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 15/20 | 0.45 |
| ▸ | HTR2B | P41595 | 8/20 | 0.45 |
| ▸ | HTR1A | P08908 | 6/20 | 0.45 |
| ▸ | HTR2A | P28223 | 12/20 | 0.44 |
| ▸ | HTR1D | P28221 | 5/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25265607 | 0.91 | HTR2C (0.43) | HTR2CHTR2BHTR1AHTR2AHTR1D | |
| SCHEMBL7001929 | 0.91 | HTR2C (0.43) | HTR2CHTR2BHTR1AHTR2AHTR1D | |
| SCHEMBL25265687 | 0.89 | HTR2C (0.41) | HTR2CHTR2BHTR1AHTR2AHTR1D | |
| SCHEMBL25197515 | 0.89 | HTR2C (0.41) | HTR2CHTR2BHTR1AHTR2AHTR1D | |
| SCHEMBL25211338 | 0.84 | HTR2C (0.38) | HTR2CHTR2BHTR1AHTR2AHTR1D | |
| SCHEMBL25220469 | 0.84 | HTR2C (0.38) | HTR2CHTR2BHTR1AHTR2AHTR1D | |
| SCHEMBL25220467 | 0.84 | HTR2C (0.38) | HTR2CHTR2BHTR1AHTR2AHTR1D | |
| SCHEMBL25211336 | 0.84 | HTR2C (0.38) | HTR2CHTR2BHTR1AHTR2AHTR1D | |
| SCHEMBL7817456 | 0.83 | HTR2C (0.40) | HTR2CHTR2BHTR1AHTR2AHTR1D | |
| SCHEMBL25520685 | 0.80 | HTR2C (0.38) | HTR2CHTR2BHTR1AHTR2AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159456-A1 | N-SUBSTITUTED INDOLES | TERRAN BIOSCIENCES INC (US) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159456-A1 | N-SUBSTITUTED INDOLES | TPH2, TPH1, AANAT | HTR2C 11/4885HTR2B 12/4885HTR1A 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.