Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 7/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25516477 | 0.85 | KDM4E (0.44) | DPP4GRIN2DGRIN2AGRIN2BGRIN2C | |
| SCHEMBL20440713 | 0.82 | CYP4F2 (0.40) | DPP4KMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL25522757 | 0.82 | GRIN2D (0.42) | DPP4GRIN2DGRIN2AGRIN2BGRIN2C | |
| SCHEMBL8293310 | 0.81 | DPP4 (0.56) | DPP4GRIN2DGRIN2AGRIN2BGRIN2C | |
| Ammonia Solution, Strong SCHEMBL11119550 | 0.80 | DPP4 (0.55) | DPP4GRIN2DGRIN2AGRIN2BGRIN2C | |
| SCHEMBL12018041 | 0.79 | KMT2A (0.57) | GRIN2DGRIN2AGRIN2BGRIN2CKMT2A | |
| SCHEMBL9559796 | 0.79 | ALDH1A1 (0.55) | HTTSMN1; SMN2CYP4F2CYP4A11 | |
| SCHEMBL16868406 | 0.79 | ALDH1A1 (0.55) | HTTSMN1; SMN2CYP4F2CYP4A11 | |
| SCHEMBL21753375 | 0.79 | SLC6A2 (0.46) | KMT2ASMN1; SMN2CYP4F2CYP4A11HPGD | |
| SCHEMBL104594 | 0.79 | GRIN2D (0.57) | GRIN2DGRIN2AGRIN2BGRIN2CKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159569-A1 | DUAL HDAC6/PROTEASOME INHIBITORS, AND METHODS OF USE THEREOF | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159569-A1 | DUAL HDAC6/PROTEASOME INHIBITORS, AND METHODS OF USE THEREOF | HDAC6, PSMG3, PSMB2 | DPP4 1682/4885GRIN2D 2603/4885GRIN2A 1908/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.